Effect of Tacrolimus Hydrate (FK506) Ointment on Spontaneous Dermatitis in NC/Nga Mice

The effect of tacrolimus hydrate (FK506) ointment on spontaneous dermatitis in NC/Nga (NC) mice was examined. FK506 ointment (0.1-1%) suppressed the development of dermatitis and was also therapeutically effective against established dermatitis. Increases in CD4-positive T cells (helper T cells), ma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Japanese journal of pharmacology 1998, Vol.76(2), pp.175-183
Hauptverfasser:	Hiroi, Jun, Sengoku, Takanori, Morita, Kyoko, Kishi, Shinichi, Sato, Sachio, Ogawa, Toshikazu, Tsudzuki, Masaoki, Matsuda, Hiroshi, Wada, Adumi, Esaki, Kozaburo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atopic dermatitis Dermatitis, Atopic - drug therapy Dermatitis, Atopic - pathology Disease Models, Animal Female FK506 Immunoglobulin E - blood Immunoglobulin G - blood Interleukin-4 Male Mast cell Mice Ointments T cell Tacrolimus - administration & dosage Tacrolimus - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!