Monoclonal antibodies block murine IL-4 receptor function

IL-4 is a cytokine which can induce B-lymphocyte proliferation, increase cell-surface Ia expression, and induce some activated B cells to differentiate and begin to secrete IgE. IL-4 binds specifically to a cell-surface receptor (IL-4R) on cells from a variety of lineages including T and B cells. In...

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Veröffentlicht in:	The Journal of immunology (1950) 1990-06, Vol.144 (11), p.4212-4217
Hauptverfasser:	Beckmann, MP, Schooley, KA, Gallis, B, Vanden Bos, T, Friend, D, Alpert, AR, Raunio, R, Prickett, KS, Baker, PE, Park, LS
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibody Affinity Antibody Specificity Biological and medical sciences Cells, Cultured Epitopes Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology In Vitro Techniques Interleukin-4 - physiology Lymphocyte Activation Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Mice Precipitin Tests Receptors, Interleukin-4 Receptors, Mitogen - immunology Receptors, Mitogen - metabolism T-Lymphocytes, Cytotoxic - immunology
Online-Zugang:	Volltext
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