Brain lipid peroxidation and antioxidant levels in fetal lambs 72 hours after asphyxia by partial umbilical cord occlusion

OBJECTIVES: The purpose of this study was to explain the role of oxidative stress in the pathogenesis of brain damage caused by intrauterine fetal asphyxia. STUDY DESIGN: Six chronically instrumented near-term fetal lambs were subjected to asphyxia by partial umbilical cord occlusion for approximate...

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Veröffentlicht in:	American journal of obstetrics and gynecology 1998-03, Vol.178 (3), p.474-478
Hauptverfasser:	Ikeda, Tomoaki, Murata, Yuji, Quilligan, Edward J., Parer, Julian T., Doi, Shigeharu, Park, Soung-Day
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals asphyxia Biological and medical sciences Brain - metabolism brain damage Constriction Diseases of mother, fetus and pregnancy Female Fetal Hypoxia - metabolism Fetal lamb Glutathione - metabolism Gynecology. Andrology. Obstetrics Lipid Peroxidation Medical sciences Oxidative Stress oxygen free radical Pregnancy. Fetus. Placenta Sheep Statistics, Nonparametric Superoxide Dismutase - metabolism Thiobarbituric Acid Reactive Substances - metabolism Umbilical Cord
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