Characterization and utilization of a monoclonal antibody inhibiting porcine natural killer cell activity for isolation of natural killer and killer cells

A mAb, porcine NK-inhibitory mAb (PNK-I) that inhibits porcine NK activity without affecting antibody-dependent cellular cytotoxicity (ADCC) has been developed. PNK-I acts at the level of the effector cell and inhibition of NK activity is independent of complement. Inhibitory effects are seen agains...

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Veröffentlicht in:	The Journal of immunology (1950) 1990-06, Vol.144 (11), p.4452-4462
Hauptverfasser:	Dato, ME, Kim, YB
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibody-Dependent Cell Cytotoxicity Antigens, Differentiation, T-Lymphocyte - analysis Biological and medical sciences Calcium - physiology CD18 Antigens Cell Separation Cytotoxic reactions (adcc reaction, cell-mediated lympholysis, complement-dependent cytotoxicity and others) Cytotoxicity, Immunologic Flow Cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology Immunity, Innate Immunobiology Immunological reactions in vitro In Vitro Techniques Killer Cells, Natural - immunology Killer Cells, Natural - ultrastructure Molecular Weight Precipitin Tests Receptors, Leukocyte-Adhesion - immunology Swine - immunology
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