Structural organization of the genes for murine and human leukemia inhibitory factor. Evolutionary conservation of coding and non-coding regions

Leukemia inhibitory factor, LIF, is a glycoprotein with multiple activities in both the adult and the embryo. LIF appears to be encoded by a unique gene in both mouse and man, although the 3'-untranslated region of the mouse LIF gene gives a complex hybridization pattern on Southern blots. The...

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Veröffentlicht in:	The Journal of biological chemistry 1990-05, Vol.265 (15), p.8833-8841
Hauptverfasser:	STAHL, J, GEARING, D. P, WILLSON, T. A, BROWN, M. A, KING, J. A, GOUGH, N. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biological and medical sciences Biological Evolution Blotting, Northern Blotting, Southern Cloning, Molecular Cytoplasm - metabolism DNA - genetics DNA - isolation & purification evolution Exons Fundamental and applied biological sciences. Psychology Gene Library Genes Genes. Genome Glycoproteins - genetics Growth Inhibitors - genetics Humans Interleukin-6 Introns Leukemia Inhibitory Factor Lymphokines Mice Molecular and cellular biology Molecular genetics Molecular Sequence Data Poly A - analysis Poly A - genetics Polymerase Chain Reaction Restriction Mapping RNA - analysis RNA - genetics RNA, Messenger - genetics Sequence Homology, Nucleic Acid Transcription, Genetic
Online-Zugang:	Volltext
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