Quality of life and psychological distress of bone marrow transplant recipients : the 'time trajectory' to recovery over the first year
The purpose of this study was to measure the trajectory of psychosocial recovery over the first year after bone marrow transplantation (BMT). BMT patients were assessed at baseline (n = 86), hospital discharge (n = 74), 100 days (n = 64) and at 1 year (n = 45). Participants completed the Functional...
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| Veröffentlicht in: | Bone marrow transplantation (Basingstoke) 1998-03, Vol.21 (5), p.477-486 |
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| creator | MCQUELLON, R. P RUSSELL, G. B RAMBO, T. D CRAVEN, B. L RADFORD, J PERRY, J. J CRUZ, J HURD, D. D |
| description | The purpose of this study was to measure the trajectory of psychosocial recovery over the first year after bone marrow transplantation (BMT). BMT patients were assessed at baseline (n = 86), hospital discharge (n = 74), 100 days (n = 64) and at 1 year (n = 45). Participants completed the Functional Assessment of Cancer Therapy-Bone Marrow Transplant Scale (FACT-BMT), the Profile of Mood States Total Mood Disturbance Scale (POMS-TMDS), the Medical Outcomes Social Support Survey (MOS-SSS), the Center for Epidemiologic Studies-Depression (CES-D) scale screener, a performance Status Rating Scale (PSR), and an interview questionnaire. The recovery trajectory in this patient population showed three distinct trends. The trajectory for distress was linear and improved over time with approximately 20% of patients continuing to have psychological distress at 1 year. Secondly, the trend for overall quality of life was parabolic, worsening at discharge, then improving at 100 days and at 1 year. However, there were individual areas of deficit at follow-up, eg fatigue, even while overall quality of life mean scores improved. Thirdly, the trend for patient concerns over time was linear and worsening. These recovery trajectories suggest psychosocial interventions before and after BMT that may prepare patients for increasing and worsening concerns even as physical well-being improves. |
| doi_str_mv | 10.1038/sj.bmt.1701115 |
| format | Article |
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P ; RUSSELL, G. B ; RAMBO, T. D ; CRAVEN, B. L ; RADFORD, J ; PERRY, J. J ; CRUZ, J ; HURD, D. D</creator><creatorcontrib>MCQUELLON, R. P ; RUSSELL, G. B ; RAMBO, T. D ; CRAVEN, B. L ; RADFORD, J ; PERRY, J. J ; CRUZ, J ; HURD, D. D</creatorcontrib><description>The purpose of this study was to measure the trajectory of psychosocial recovery over the first year after bone marrow transplantation (BMT). BMT patients were assessed at baseline (n = 86), hospital discharge (n = 74), 100 days (n = 64) and at 1 year (n = 45). Participants completed the Functional Assessment of Cancer Therapy-Bone Marrow Transplant Scale (FACT-BMT), the Profile of Mood States Total Mood Disturbance Scale (POMS-TMDS), the Medical Outcomes Social Support Survey (MOS-SSS), the Center for Epidemiologic Studies-Depression (CES-D) scale screener, a performance Status Rating Scale (PSR), and an interview questionnaire. The recovery trajectory in this patient population showed three distinct trends. The trajectory for distress was linear and improved over time with approximately 20% of patients continuing to have psychological distress at 1 year. Secondly, the trend for overall quality of life was parabolic, worsening at discharge, then improving at 100 days and at 1 year. However, there were individual areas of deficit at follow-up, eg fatigue, even while overall quality of life mean scores improved. Thirdly, the trend for patient concerns over time was linear and worsening. These recovery trajectories suggest psychosocial interventions before and after BMT that may prepare patients for increasing and worsening concerns even as physical well-being improves.</description><identifier>ISSN: 0268-3369</identifier><identifier>EISSN: 1476-5365</identifier><identifier>DOI: 10.1038/sj.bmt.1701115</identifier><identifier>PMID: 9535040</identifier><identifier>CODEN: BMTRE9</identifier><language>eng</language><publisher>Basingstoke: Nature Publishing Group</publisher><subject>Adult ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Bone cancer ; Bone marrow ; Bone marrow transplantation ; Bone Marrow Transplantation - psychology ; Bone marrow, stem cells transplantation. Graft versus host reaction ; Epidemiology ; Female ; Fundamental and applied biological sciences. Psychology ; Humans ; Longitudinal Studies ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Mood ; Patient Satisfaction ; Patients ; Prospective Studies ; Psychological stress ; Psychology and medicine ; Psychology. Psychoanalysis. Psychiatry ; Psychology. Psychophysiology ; Quality of Life ; Recovery ; Social interactions ; Social Support ; Stem cell transplantation ; Time Factors ; Trajectory measurement ; Transfusions. Complications. Transfusion reactions. 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P</creatorcontrib><creatorcontrib>RUSSELL, G. B</creatorcontrib><creatorcontrib>RAMBO, T. D</creatorcontrib><creatorcontrib>CRAVEN, B. L</creatorcontrib><creatorcontrib>RADFORD, J</creatorcontrib><creatorcontrib>PERRY, J. J</creatorcontrib><creatorcontrib>CRUZ, J</creatorcontrib><creatorcontrib>HURD, D. D</creatorcontrib><title>Quality of life and psychological distress of bone marrow transplant recipients : the 'time trajectory' to recovery over the first year</title><title>Bone marrow transplantation (Basingstoke)</title><addtitle>Bone Marrow Transplant</addtitle><description>The purpose of this study was to measure the trajectory of psychosocial recovery over the first year after bone marrow transplantation (BMT). BMT patients were assessed at baseline (n = 86), hospital discharge (n = 74), 100 days (n = 64) and at 1 year (n = 45). 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These recovery trajectories suggest psychosocial interventions before and after BMT that may prepare patients for increasing and worsening concerns even as physical well-being improves.</description><subject>Adult</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Bone cancer</subject><subject>Bone marrow</subject><subject>Bone marrow transplantation</subject><subject>Bone Marrow Transplantation - psychology</subject><subject>Bone marrow, stem cells transplantation. Graft versus host reaction</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mood</subject><subject>Patient Satisfaction</subject><subject>Patients</subject><subject>Prospective Studies</subject><subject>Psychological stress</subject><subject>Psychology and medicine</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. Psychophysiology</subject><subject>Quality of Life</subject><subject>Recovery</subject><subject>Social interactions</subject><subject>Social Support</subject><subject>Stem cell transplantation</subject><subject>Time Factors</subject><subject>Trajectory measurement</subject><subject>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><subject>Transplantation</subject><subject>Trends</subject><subject>Well being</subject><issn>0268-3369</issn><issn>1476-5365</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkctq3TAQhkVpSE9Ou-2uIGhoVj7VxfKluxJ6CQRKIXshy-NGxrZcjZziJ-hrR25MFt3MLOab2_8T8pazE2ey-oj9qRnjiZeMc65ekAPPyyJTslAvyYGJosqkLOpX5AKxZ4znOVPn5LxWUrGcHcjfn4sZXFyp7-jgOqBmaumMq733g__lrBlo6zAGQNyQxk9ARxOC_0NjMBPOg5kiDWDd7GCKSD_ReA_0KroRNqIHG31Yr2j0G-UfIKRdKf7DOhcw0hVMeE3OOjMgvNnzkdx9_XJ3_T27_fHt5vrzbWZzJWOmmBAVEy0zJdRtY7uuAiVBGVaC4HXRsPRgY0E0bVXlRW1tlUtWN6VtGylbeSQfnsbOwf9eAKMeHVoY0hfgF9RlXZZSJXWO5P1_YO-XMKXTtChywZWsxUadnigbPGKATs_BJXlWzZne7NHY62SP3u1JDe_2sUszQvuM736k-uVeN5i075LE1uEzJnhZK8HlI2fgmo4</recordid><startdate>19980301</startdate><enddate>19980301</enddate><creator>MCQUELLON, R. P</creator><creator>RUSSELL, G. B</creator><creator>RAMBO, T. D</creator><creator>CRAVEN, B. 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P</au><au>RUSSELL, G. B</au><au>RAMBO, T. D</au><au>CRAVEN, B. L</au><au>RADFORD, J</au><au>PERRY, J. J</au><au>CRUZ, J</au><au>HURD, D. D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quality of life and psychological distress of bone marrow transplant recipients : the 'time trajectory' to recovery over the first year</atitle><jtitle>Bone marrow transplantation (Basingstoke)</jtitle><addtitle>Bone Marrow Transplant</addtitle><date>1998-03-01</date><risdate>1998</risdate><volume>21</volume><issue>5</issue><spage>477</spage><epage>486</epage><pages>477-486</pages><issn>0268-3369</issn><eissn>1476-5365</eissn><coden>BMTRE9</coden><abstract>The purpose of this study was to measure the trajectory of psychosocial recovery over the first year after bone marrow transplantation (BMT). BMT patients were assessed at baseline (n = 86), hospital discharge (n = 74), 100 days (n = 64) and at 1 year (n = 45). Participants completed the Functional Assessment of Cancer Therapy-Bone Marrow Transplant Scale (FACT-BMT), the Profile of Mood States Total Mood Disturbance Scale (POMS-TMDS), the Medical Outcomes Social Support Survey (MOS-SSS), the Center for Epidemiologic Studies-Depression (CES-D) scale screener, a performance Status Rating Scale (PSR), and an interview questionnaire. The recovery trajectory in this patient population showed three distinct trends. The trajectory for distress was linear and improved over time with approximately 20% of patients continuing to have psychological distress at 1 year. Secondly, the trend for overall quality of life was parabolic, worsening at discharge, then improving at 100 days and at 1 year. However, there were individual areas of deficit at follow-up, eg fatigue, even while overall quality of life mean scores improved. Thirdly, the trend for patient concerns over time was linear and worsening. 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| identifier | ISSN: 0268-3369 |
| ispartof | Bone marrow transplantation (Basingstoke), 1998-03, Vol.21 (5), p.477-486 |
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| subjects | Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone cancer Bone marrow Bone marrow transplantation Bone Marrow Transplantation - psychology Bone marrow, stem cells transplantation. Graft versus host reaction Epidemiology Female Fundamental and applied biological sciences. Psychology Humans Longitudinal Studies Male Medical sciences Middle Aged Miscellaneous Mood Patient Satisfaction Patients Prospective Studies Psychological stress Psychology and medicine Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Quality of Life Recovery Social interactions Social Support Stem cell transplantation Time Factors Trajectory measurement Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Trends Well being |
| title | Quality of life and psychological distress of bone marrow transplant recipients : the 'time trajectory' to recovery over the first year |
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