Chronic Electroconvulsive Seizures Down–Regulate Expression of the Immediate‐Early Genes c‐fos and c‐jun in Rat Cerebral Cortex

: Acute seizures and other stimuli that increase neuronal activity cause a rapid induction of the immediate‐early genes c‐fos and c‐jun, also referred to as nuclear proto‐on‐cogenes, in the nervous system. In the present study, rats were administered one or more electroconvulsive seizures (ECS) and...

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Veröffentlicht in:	Journal of neurochemistry 1990-06, Vol.54 (6), p.1920-1925
Hauptverfasser:	Winston, Sheryl M., Hayward, Michael D., Nestler, Eric J., Duman, Ronald S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressants Biological and medical sciences Cerebral Cortex - physiology Chronic Disease Chronic electroconvulsive seizure c‐fos c‐jun DNA-Binding Proteins - genetics Electroshock Gene Expression Regulation Immediate‐early genes Immunoblotting Male Medical sciences mRNA Nervous system involvement in other diseases. Miscellaneous Neurology Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-fos Proto-Oncogene Proteins c-jun Rats Rats, Inbred Strains Seizures - etiology Seizures - genetics Seizures - metabolism Transcription Factors - genetics
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