Nucleolar Localization of Mouse Mammary Tumor Virus Proteins in T-Cell Lymphomas

To characterize novel proteins expressed in lymphoma cells, monoclonal antibodies (MAbs) were raised against variant S49 mouse lymphoma cells. Immunoperoxidase analysis with a specific MAb, named M-66, revealed nuclear localization with prominent staining in the nucleoli of both tumorigenic (T-63) c...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1998-03, Vol.242 (2), p.246-254
Hauptverfasser:	Hoch-Marchaim, Hagit, Hasson, Tsuri, Rorman, Efrat, Cohen, Shulamit, Hochman, Jacob
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Monoclonal Antigens, Viral, Tumor - metabolism Blotting, Western Cell Membrane - metabolism Cell Nucleolus - metabolism Cell Nucleolus - virology Cytoplasm - metabolism DNA, Neoplasm - analysis Gene Library Immunoenzyme Techniques Lymphoma, T-Cell - metabolism Lymphoma, T-Cell - ultrastructure Lymphoma, T-Cell - virology Mammary Tumor Virus, Mouse - metabolism Mice Mice, Inbred C57BL Microscopy, Immunoelectron Molecular Sequence Data Nuclear Proteins - metabolism Precipitin Tests Protein Biosynthesis Sequence Homology, Amino Acid Transcription, Genetic Tumor Cells, Cultured Viral Envelope Proteins - genetics Viral Envelope Proteins - metabolism
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