Apolipoprotein E4 reduces risk of diabetic nephropathy in patients with NIDDM

Hypercholesterolemia is a major determinant of the decline of renal function in patients with diabetes. Apolipoprotein E polymorphism may influence the metabolism of lipoprotein in diabetic patients. The purpose of this study was to investigate the association between genetic polymorphisms in apolip...

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Veröffentlicht in:	American journal of kidney diseases 1998-04, Vol.31 (4), p.666-673
Hauptverfasser:	Kimura, H, Suzuki, Y, Gejyo, F, Karasawa, R, Miyazaki, R, Suzuki, S, Arakawa, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Apolipoprotein E4 Apolipoproteins E - blood Apolipoproteins E - genetics Associated diseases and complications Biological and medical sciences Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Diabetic Nephropathies - blood Diabetic Nephropathies - etiology Diabetic Nephropathies - genetics Disease Progression DNA - blood Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Genotype Humans Kidney Failure, Chronic - blood Kidney Failure, Chronic - genetics Kidney Failure, Chronic - therapy Male Medical sciences Middle Aged Phenotype Polymorphism, Genetic - genetics Renal Dialysis Risk Factors Time Factors
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