Prostacyclin producing activity of human umbilical blood vessels in adrenergic innervated and non-innervated portions
The present experiment was performed in order to clarify the significance of prostacyclin (PGI 2) in the regulation of human umbilical blood flow. Distribution of adrenergic nerve fibers in umbilical cord was examined by means of a modification of the glyoxylic acid fluorescence histochemical techni...
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| Veröffentlicht in: | Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 1990-03, Vol.39 (3), p.239-245 |
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| container_title | Prostaglandins, leukotrienes and essential fatty acids |
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| creator | Kawano, Michihisa Mori, Norimasa |
| description | The present experiment was performed in order to clarify the significance of prostacyclin (PGI
2) in the regulation of human umbilical blood flow. Distribution of adrenergic nerve fibers in umbilical cord was examined by means of a modification of the glyoxylic acid fluorescence histochemical technique. PGI
2 producing activity in various portions of umbilical blood vessels was measured by platelet bioassay. Adrenergic nerve fibers were observed only in the region surrounding umbilical arteries at the fetal end of the cord. PGI
2 producing activity of umbilical arteries was significantly lower in the innervated region than in the non-innervated region. There were no significant regional differences in umbilical vein which has no adrenergic innervation.
The relationship between vascular PGI
2 producing activity and adrenergic innervation, and the significance of PGI
2 in the regulation of human umbilical blood flow are discussed. |
| doi_str_mv | 10.1016/0952-3278(90)90079-Z |
| format | Article |
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2) in the regulation of human umbilical blood flow. Distribution of adrenergic nerve fibers in umbilical cord was examined by means of a modification of the glyoxylic acid fluorescence histochemical technique. PGI
2 producing activity in various portions of umbilical blood vessels was measured by platelet bioassay. Adrenergic nerve fibers were observed only in the region surrounding umbilical arteries at the fetal end of the cord. PGI
2 producing activity of umbilical arteries was significantly lower in the innervated region than in the non-innervated region. There were no significant regional differences in umbilical vein which has no adrenergic innervation.
The relationship between vascular PGI
2 producing activity and adrenergic innervation, and the significance of PGI
2 in the regulation of human umbilical blood flow are discussed.</description><identifier>ISSN: 0952-3278</identifier><identifier>EISSN: 1532-2823</identifier><identifier>DOI: 10.1016/0952-3278(90)90079-Z</identifier><identifier>PMID: 2110680</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adrenergic Fibers - metabolism ; Adrenergic Fibers - ultrastructure ; Biological and medical sciences ; Epoprostenol - antagonists & inhibitors ; Epoprostenol - metabolism ; Female ; Fundamental and applied biological sciences. Psychology ; Humans ; Indomethacin - pharmacology ; Kinetics ; Microscopy, Fluorescence ; Pregnancy ; Prostaglandins. Arachidonic acid metabolites ; Regional Blood Flow ; Umbilical Arteries - metabolism ; Umbilical Arteries - ultrastructure ; Umbilical Cord - blood supply ; Umbilical Cord - innervation ; Umbilical Cord - metabolism ; Umbilical Cord - ultrastructure ; Umbilical Veins - metabolism ; Umbilical Veins - ultrastructure ; Vertebrates: endocrinology</subject><ispartof>Prostaglandins, leukotrienes and essential fatty acids, 1990-03, Vol.39 (3), p.239-245</ispartof><rights>1990</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c301t-87fd4c099c67c50a71a2d6efb977d57df8d02fbf69036d35fb56f4da64cab8623</citedby><cites>FETCH-LOGICAL-c301t-87fd4c099c67c50a71a2d6efb977d57df8d02fbf69036d35fb56f4da64cab8623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/095232789090079Z$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6830505$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2110680$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kawano, Michihisa</creatorcontrib><creatorcontrib>Mori, Norimasa</creatorcontrib><title>Prostacyclin producing activity of human umbilical blood vessels in adrenergic innervated and non-innervated portions</title><title>Prostaglandins, leukotrienes and essential fatty acids</title><addtitle>Prostaglandins Leukot Essent Fatty Acids</addtitle><description>The present experiment was performed in order to clarify the significance of prostacyclin (PGI
2) in the regulation of human umbilical blood flow. Distribution of adrenergic nerve fibers in umbilical cord was examined by means of a modification of the glyoxylic acid fluorescence histochemical technique. PGI
2 producing activity in various portions of umbilical blood vessels was measured by platelet bioassay. Adrenergic nerve fibers were observed only in the region surrounding umbilical arteries at the fetal end of the cord. PGI
2 producing activity of umbilical arteries was significantly lower in the innervated region than in the non-innervated region. There were no significant regional differences in umbilical vein which has no adrenergic innervation.
The relationship between vascular PGI
2 producing activity and adrenergic innervation, and the significance of PGI
2 in the regulation of human umbilical blood flow are discussed.</description><subject>Adrenergic Fibers - metabolism</subject><subject>Adrenergic Fibers - ultrastructure</subject><subject>Biological and medical sciences</subject><subject>Epoprostenol - antagonists & inhibitors</subject><subject>Epoprostenol - metabolism</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Indomethacin - pharmacology</subject><subject>Kinetics</subject><subject>Microscopy, Fluorescence</subject><subject>Pregnancy</subject><subject>Prostaglandins. Arachidonic acid metabolites</subject><subject>Regional Blood Flow</subject><subject>Umbilical Arteries - metabolism</subject><subject>Umbilical Arteries - ultrastructure</subject><subject>Umbilical Cord - blood supply</subject><subject>Umbilical Cord - innervation</subject><subject>Umbilical Cord - metabolism</subject><subject>Umbilical Cord - ultrastructure</subject><subject>Umbilical Veins - metabolism</subject><subject>Umbilical Veins - ultrastructure</subject><subject>Vertebrates: endocrinology</subject><issn>0952-3278</issn><issn>1532-2823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM9rFDEUx0NR6rb2P6iQg0h7GH1JZpLJpSDFVqGgB730EjL5USMzyZrMLOx_b7a7LJ56ekne5_t4-SB0SeAjAcI_gexow6joryRcSwAhm8cTtCIdow3tKXuFVkfkDTor5Q8AUELaU3RaC_AeVmj5kVOZtdmaMUS8zskuJsQnrM0cNmHe4uTx72XSES_TEMZg9IiHMSWLN64UNxZcY9pmF11-Cqbe6mGjZ2exjhbHFJv_ntYpzyHF8ha99nos7uJQz9Gvuy8_b782D9_vv91-fmgMAzI3vfC2NSCl4cJ0oAXR1HLnBymE7YT1vQXqB88lMG5Z54eO-9Zq3ho99Jyyc_RhP7d-7O_iyqymUIwbRx1dWooSUnBKGatguwdN1VGy82qdw6TzVhFQO9tqp1LtVCoJ6tm2eqyxd4f5yzA5ewwd9Nb--0Nfl2rOZx1NKEeM9ww66Cp2s8eqT7cJLqtigovG2ZCdmZVN4eU9_gGdap7H</recordid><startdate>199003</startdate><enddate>199003</enddate><creator>Kawano, Michihisa</creator><creator>Mori, Norimasa</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199003</creationdate><title>Prostacyclin producing activity of human umbilical blood vessels in adrenergic innervated and non-innervated portions</title><author>Kawano, Michihisa ; Mori, Norimasa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c301t-87fd4c099c67c50a71a2d6efb977d57df8d02fbf69036d35fb56f4da64cab8623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Adrenergic Fibers - metabolism</topic><topic>Adrenergic Fibers - ultrastructure</topic><topic>Biological and medical sciences</topic><topic>Epoprostenol - antagonists & inhibitors</topic><topic>Epoprostenol - metabolism</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Indomethacin - pharmacology</topic><topic>Kinetics</topic><topic>Microscopy, Fluorescence</topic><topic>Pregnancy</topic><topic>Prostaglandins. Arachidonic acid metabolites</topic><topic>Regional Blood Flow</topic><topic>Umbilical Arteries - metabolism</topic><topic>Umbilical Arteries - ultrastructure</topic><topic>Umbilical Cord - blood supply</topic><topic>Umbilical Cord - innervation</topic><topic>Umbilical Cord - metabolism</topic><topic>Umbilical Cord - ultrastructure</topic><topic>Umbilical Veins - metabolism</topic><topic>Umbilical Veins - ultrastructure</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kawano, Michihisa</creatorcontrib><creatorcontrib>Mori, Norimasa</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Prostaglandins, leukotrienes and essential fatty acids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kawano, Michihisa</au><au>Mori, Norimasa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prostacyclin producing activity of human umbilical blood vessels in adrenergic innervated and non-innervated portions</atitle><jtitle>Prostaglandins, leukotrienes and essential fatty acids</jtitle><addtitle>Prostaglandins Leukot Essent Fatty Acids</addtitle><date>1990-03</date><risdate>1990</risdate><volume>39</volume><issue>3</issue><spage>239</spage><epage>245</epage><pages>239-245</pages><issn>0952-3278</issn><eissn>1532-2823</eissn><abstract>The present experiment was performed in order to clarify the significance of prostacyclin (PGI
2) in the regulation of human umbilical blood flow. Distribution of adrenergic nerve fibers in umbilical cord was examined by means of a modification of the glyoxylic acid fluorescence histochemical technique. PGI
2 producing activity in various portions of umbilical blood vessels was measured by platelet bioassay. Adrenergic nerve fibers were observed only in the region surrounding umbilical arteries at the fetal end of the cord. PGI
2 producing activity of umbilical arteries was significantly lower in the innervated region than in the non-innervated region. There were no significant regional differences in umbilical vein which has no adrenergic innervation.
The relationship between vascular PGI
2 producing activity and adrenergic innervation, and the significance of PGI
2 in the regulation of human umbilical blood flow are discussed.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>2110680</pmid><doi>10.1016/0952-3278(90)90079-Z</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0952-3278 |
| ispartof | Prostaglandins, leukotrienes and essential fatty acids, 1990-03, Vol.39 (3), p.239-245 |
| issn | 0952-3278 1532-2823 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adrenergic Fibers - metabolism Adrenergic Fibers - ultrastructure Biological and medical sciences Epoprostenol - antagonists & inhibitors Epoprostenol - metabolism Female Fundamental and applied biological sciences. Psychology Humans Indomethacin - pharmacology Kinetics Microscopy, Fluorescence Pregnancy Prostaglandins. Arachidonic acid metabolites Regional Blood Flow Umbilical Arteries - metabolism Umbilical Arteries - ultrastructure Umbilical Cord - blood supply Umbilical Cord - innervation Umbilical Cord - metabolism Umbilical Cord - ultrastructure Umbilical Veins - metabolism Umbilical Veins - ultrastructure Vertebrates: endocrinology |
| title | Prostacyclin producing activity of human umbilical blood vessels in adrenergic innervated and non-innervated portions |
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