Odontogenic ghost cell tumor: A case report with cytologic findings

Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1)...

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Veröffentlicht in:Diagnostic cytopathology 1998-03, Vol.18 (3), p.199-203
Hauptverfasser: Stone, Chad H., Gaba, Arthur R., Benninger, Michael S., Zarbo, Richard J.
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container_title Diagnostic cytopathology
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creator Stone, Chad H.
Gaba, Arthur R.
Benninger, Michael S.
Zarbo, Richard J.
description Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1) tissue fragments with basaloid epithelial cells, (2) “ghost” cells, (3) scattered multinucleated giant cells, (4) rare, eosinophilic, densely hyalinized “dentinoid” material in close association with the basaloid cells, and (5) calcific debris. The aspirate was diagnosed as “consistent with odontogenic ghost cell tumor.” The cytologic features of odontogenic ghost cell tumor, as described, closely parallel the major histologic findings in this rare tumor. The differential diagnoses include other odontogenic tumors, squamous cell carcinoma, basaloid cell tumors of the salivary gland, and pilomatrixoma. Diagn. Cytopathol. 1998;18:199–203. © 1998 Wiley‐Liss, Inc.
doi_str_mv 10.1002/(SICI)1097-0339(199803)18:3<199::AID-DC7>3.0.CO;2-9
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Cytopathol</addtitle><description>Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1) tissue fragments with basaloid epithelial cells, (2) “ghost” cells, (3) scattered multinucleated giant cells, (4) rare, eosinophilic, densely hyalinized “dentinoid” material in close association with the basaloid cells, and (5) calcific debris. The aspirate was diagnosed as “consistent with odontogenic ghost cell tumor.” The cytologic features of odontogenic ghost cell tumor, as described, closely parallel the major histologic findings in this rare tumor. The differential diagnoses include other odontogenic tumors, squamous cell carcinoma, basaloid cell tumors of the salivary gland, and pilomatrixoma. Diagn. Cytopathol. 1998;18:199–203. © 1998 Wiley‐Liss, Inc.</description><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Carcinoma, Basosquamous - pathology</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>dentinogenic</subject><subject>Diagnosis, Differential</subject><subject>Facial bones, jaws, teeth, parodontium: diseases, semeiology</subject><subject>ghost cell</subject><subject>Gorlin cyst</subject><subject>Humans</subject><subject>Male</subject><subject>Maxillary Neoplasms - pathology</subject><subject>Maxillary Neoplasms - therapy</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>odontogenic</subject><subject>Odontogenic Cyst, Calcifying - pathology</subject><subject>Odontogenic Cyst, Calcifying - therapy</subject><subject>Otorhinolaryngology. 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Stomatology</topic><topic>Pilomatrixoma - pathology</topic><topic>Salivary Gland Neoplasms - pathology</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stone, Chad H.</creatorcontrib><creatorcontrib>Gaba, Arthur R.</creatorcontrib><creatorcontrib>Benninger, Michael S.</creatorcontrib><creatorcontrib>Zarbo, Richard J.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diagnostic cytopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stone, Chad H.</au><au>Gaba, Arthur R.</au><au>Benninger, Michael S.</au><au>Zarbo, Richard J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Odontogenic ghost cell tumor: A case report with cytologic findings</atitle><jtitle>Diagnostic cytopathology</jtitle><addtitle>Diagn. 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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Biological and medical sciences
Biopsy, Needle
Carcinoma, Basosquamous - pathology
Carcinoma, Squamous Cell - pathology
dentinogenic
Diagnosis, Differential
Facial bones, jaws, teeth, parodontium: diseases, semeiology
ghost cell
Gorlin cyst
Humans
Male
Maxillary Neoplasms - pathology
Maxillary Neoplasms - therapy
Medical sciences
Middle Aged
odontogenic
Odontogenic Cyst, Calcifying - pathology
Odontogenic Cyst, Calcifying - therapy
Otorhinolaryngology. Stomatology
Pilomatrixoma - pathology
Salivary Gland Neoplasms - pathology
Tumors
title Odontogenic ghost cell tumor: A case report with cytologic findings
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