Odontogenic ghost cell tumor: A case report with cytologic findings
Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1)...
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Veröffentlicht in: | Diagnostic cytopathology 1998-03, Vol.18 (3), p.199-203 |
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description | Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1) tissue fragments with basaloid epithelial cells, (2) “ghost” cells, (3) scattered multinucleated giant cells, (4) rare, eosinophilic, densely hyalinized “dentinoid” material in close association with the basaloid cells, and (5) calcific debris. The aspirate was diagnosed as “consistent with odontogenic ghost cell tumor.” The cytologic features of odontogenic ghost cell tumor, as described, closely parallel the major histologic findings in this rare tumor. The differential diagnoses include other odontogenic tumors, squamous cell carcinoma, basaloid cell tumors of the salivary gland, and pilomatrixoma. Diagn. Cytopathol. 1998;18:199–203. © 1998 Wiley‐Liss, Inc. |
doi_str_mv | 10.1002/(SICI)1097-0339(199803)18:3<199::AID-DC7>3.0.CO;2-9 |
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We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1) tissue fragments with basaloid epithelial cells, (2) “ghost” cells, (3) scattered multinucleated giant cells, (4) rare, eosinophilic, densely hyalinized “dentinoid” material in close association with the basaloid cells, and (5) calcific debris. The aspirate was diagnosed as “consistent with odontogenic ghost cell tumor.” The cytologic features of odontogenic ghost cell tumor, as described, closely parallel the major histologic findings in this rare tumor. The differential diagnoses include other odontogenic tumors, squamous cell carcinoma, basaloid cell tumors of the salivary gland, and pilomatrixoma. Diagn. Cytopathol. 1998;18:199–203. © 1998 Wiley‐Liss, Inc.</description><identifier>ISSN: 8755-1039</identifier><identifier>EISSN: 1097-0339</identifier><identifier>DOI: 10.1002/(SICI)1097-0339(199803)18:3<199::AID-DC7>3.0.CO;2-9</identifier><identifier>PMID: 9523138</identifier><identifier>CODEN: DICYE7</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Biological and medical sciences ; Biopsy, Needle ; Carcinoma, Basosquamous - pathology ; Carcinoma, Squamous Cell - pathology ; dentinogenic ; Diagnosis, Differential ; Facial bones, jaws, teeth, parodontium: diseases, semeiology ; ghost cell ; Gorlin cyst ; Humans ; Male ; Maxillary Neoplasms - pathology ; Maxillary Neoplasms - therapy ; Medical sciences ; Middle Aged ; odontogenic ; Odontogenic Cyst, Calcifying - pathology ; Odontogenic Cyst, Calcifying - therapy ; Otorhinolaryngology. Stomatology ; Pilomatrixoma - pathology ; Salivary Gland Neoplasms - pathology ; Tumors</subject><ispartof>Diagnostic cytopathology, 1998-03, Vol.18 (3), p.199-203</ispartof><rights>Copyright © 1998 Wiley‐Liss, Inc.</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4247-6f20b04d42c206c77976ada691a8b1a0cd693b0b641251a614a0ec827be3cd5f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2F%28SICI%291097-0339%28199803%2918%3A3%3C199%3A%3AAID-DC7%3E3.0.CO%3B2-9$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2F%28SICI%291097-0339%28199803%2918%3A3%3C199%3A%3AAID-DC7%3E3.0.CO%3B2-9$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2171311$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9523138$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stone, Chad H.</creatorcontrib><creatorcontrib>Gaba, Arthur R.</creatorcontrib><creatorcontrib>Benninger, Michael S.</creatorcontrib><creatorcontrib>Zarbo, Richard J.</creatorcontrib><title>Odontogenic ghost cell tumor: A case report with cytologic findings</title><title>Diagnostic cytopathology</title><addtitle>Diagn. Cytopathol</addtitle><description>Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1) tissue fragments with basaloid epithelial cells, (2) “ghost” cells, (3) scattered multinucleated giant cells, (4) rare, eosinophilic, densely hyalinized “dentinoid” material in close association with the basaloid cells, and (5) calcific debris. The aspirate was diagnosed as “consistent with odontogenic ghost cell tumor.” The cytologic features of odontogenic ghost cell tumor, as described, closely parallel the major histologic findings in this rare tumor. The differential diagnoses include other odontogenic tumors, squamous cell carcinoma, basaloid cell tumors of the salivary gland, and pilomatrixoma. Diagn. Cytopathol. 1998;18:199–203. © 1998 Wiley‐Liss, Inc.</description><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Carcinoma, Basosquamous - pathology</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>dentinogenic</subject><subject>Diagnosis, Differential</subject><subject>Facial bones, jaws, teeth, parodontium: diseases, semeiology</subject><subject>ghost cell</subject><subject>Gorlin cyst</subject><subject>Humans</subject><subject>Male</subject><subject>Maxillary Neoplasms - pathology</subject><subject>Maxillary Neoplasms - therapy</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>odontogenic</subject><subject>Odontogenic Cyst, Calcifying - pathology</subject><subject>Odontogenic Cyst, Calcifying - therapy</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Pilomatrixoma - pathology</subject><subject>Salivary Gland Neoplasms - pathology</subject><subject>Tumors</subject><issn>8755-1039</issn><issn>1097-0339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkNFq2zAUhsXY6LJujzDwxRjthbMjybasdAyCs7WBskDascuDLMupN8fKJIc2b18Zh9z0Ylc6h_Px6-cj5IrClAKwLxd3y2J5SUGKGDiXF1TKHPglzWf8a5hns_lyES8K8Y1PYVqsrlgsX5HJiX9NJrlI05gCl2_JO-__AIBkNDsjZzJlnPJ8QopVZbvebkzX6GjzYH0fadO2Ub_fWjeL5pFW3kTO7Kzro8emf4j0obet3QS8brqq6Tb-PXlTq9abD8f3nPz68f2-uIlvV9fLYn4b64QlIs5qBiUkVcI0g0wLIUWmKpVJqvKSKtBVJnkJZZZQllKV0USB0TkTpeG6Smt-Tj6PuTtn_-2N73Hb-KGt6ozdewyBaZ4AC-DdCGpnvXemxp1rtsodkAIOahEHtTiowkEVjmqR5siHGTGoxaA2rIDFChnKkPrx-P2-3JrqlHl0Ge6fjnfltWprpzrd-BPGqKCc0oCtR-yxac3hRbP_FHvZa1hDaDyGNr43T6dQ5f5iJrhI8ffPa0zuk3R9s8hxzZ8BIRutBQ</recordid><startdate>199803</startdate><enddate>199803</enddate><creator>Stone, Chad H.</creator><creator>Gaba, Arthur R.</creator><creator>Benninger, Michael S.</creator><creator>Zarbo, Richard J.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199803</creationdate><title>Odontogenic ghost cell tumor: A case report with cytologic findings</title><author>Stone, Chad H. ; Gaba, Arthur R. ; Benninger, Michael S. ; Zarbo, Richard J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4247-6f20b04d42c206c77976ada691a8b1a0cd693b0b641251a614a0ec827be3cd5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Biological and medical sciences</topic><topic>Biopsy, Needle</topic><topic>Carcinoma, Basosquamous - pathology</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>dentinogenic</topic><topic>Diagnosis, Differential</topic><topic>Facial bones, jaws, teeth, parodontium: diseases, semeiology</topic><topic>ghost cell</topic><topic>Gorlin cyst</topic><topic>Humans</topic><topic>Male</topic><topic>Maxillary Neoplasms - pathology</topic><topic>Maxillary Neoplasms - therapy</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>odontogenic</topic><topic>Odontogenic Cyst, Calcifying - pathology</topic><topic>Odontogenic Cyst, Calcifying - therapy</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Pilomatrixoma - pathology</topic><topic>Salivary Gland Neoplasms - pathology</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stone, Chad H.</creatorcontrib><creatorcontrib>Gaba, Arthur R.</creatorcontrib><creatorcontrib>Benninger, Michael S.</creatorcontrib><creatorcontrib>Zarbo, Richard J.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diagnostic cytopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stone, Chad H.</au><au>Gaba, Arthur R.</au><au>Benninger, Michael S.</au><au>Zarbo, Richard J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Odontogenic ghost cell tumor: A case report with cytologic findings</atitle><jtitle>Diagnostic cytopathology</jtitle><addtitle>Diagn. Cytopathol</addtitle><date>1998-03</date><risdate>1998</risdate><volume>18</volume><issue>3</issue><spage>199</spage><epage>203</epage><pages>199-203</pages><issn>8755-1039</issn><eissn>1097-0339</eissn><coden>DICYE7</coden><abstract>Odontogenic ghost cell tumor is a rare, neoplastic form of calcifying odontogenic cyst (Gorlin cyst) whose cytologic features have not been previously reported. We present a case of odontogenic ghost cell tumor diagnosed by fine‐needle aspiration biopsy (FNAB). The aspirate was characterized by (1) tissue fragments with basaloid epithelial cells, (2) “ghost” cells, (3) scattered multinucleated giant cells, (4) rare, eosinophilic, densely hyalinized “dentinoid” material in close association with the basaloid cells, and (5) calcific debris. The aspirate was diagnosed as “consistent with odontogenic ghost cell tumor.” The cytologic features of odontogenic ghost cell tumor, as described, closely parallel the major histologic findings in this rare tumor. The differential diagnoses include other odontogenic tumors, squamous cell carcinoma, basaloid cell tumors of the salivary gland, and pilomatrixoma. Diagn. Cytopathol. 1998;18:199–203. © 1998 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>9523138</pmid><doi>10.1002/(SICI)1097-0339(199803)18:3<199::AID-DC7>3.0.CO;2-9</doi><tpages>5</tpages></addata></record> |
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subjects | Biological and medical sciences Biopsy, Needle Carcinoma, Basosquamous - pathology Carcinoma, Squamous Cell - pathology dentinogenic Diagnosis, Differential Facial bones, jaws, teeth, parodontium: diseases, semeiology ghost cell Gorlin cyst Humans Male Maxillary Neoplasms - pathology Maxillary Neoplasms - therapy Medical sciences Middle Aged odontogenic Odontogenic Cyst, Calcifying - pathology Odontogenic Cyst, Calcifying - therapy Otorhinolaryngology. Stomatology Pilomatrixoma - pathology Salivary Gland Neoplasms - pathology Tumors |
title | Odontogenic ghost cell tumor: A case report with cytologic findings |
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