Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors

Adeno-associated viral (AAV) vectors have much promise in gene therapy. Among the many properties that make AAV an ideal vector for gene therapy are its ability to infect both dividing and nondividing cells and the longevity of expression in tissues such as brain, skeletal muscle, and liver. However...

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Veröffentlicht in:Human gene therapy 1998-03, Vol.9 (4), p.477-485
Hauptverfasser: Manning, W C, Zhou, S, Bland, M P, Escobedo, J A, Dwarki, V
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Sprache:eng
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