Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src

Chronic granulomatous diseases (CGDs) are characterized by recurrent infections resulting from impaired superoxide production by a phagocytic cell, nicotinamide adenine dinucleotide phosphate (reduced) (NADPH) oxidase. Complementary DNAs were cloned that encode the 67-kilodalton (kD) cytosolic oxida...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1990-05, Vol.248 (4956), p.727-727
Hauptverfasser: Leto, T L, Lomax, K J, Volpp, B D, Nunoi, H, Sechler, J M, Nauseef, W M, Clark, R A, Gallin, J I, Malech, H L
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Sprache:eng
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