Fatty acid alterations and carboxylase deficiencies in the skin of biotin-deficient rats

Full-thickness biopsies of haired and alopecic skin of biotin-deficient rats had less subcutaneous fat and showed lipophilic follicular plugging, vascular engorgement, epidermal hyperplasia, and abnormal keratinization. Mean activities of the three mitochondrial biotin-dependent carboxylases in the...

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Veröffentlicht in:	The American journal of clinical nutrition 1990-05, Vol.51 (5), p.853-858
Hauptverfasser:	Proud, VK, Rizzo, WB, Patterson, JW, Heard, GS, Wolf, B
Format:	Artikel
Sprache:	eng
Schlagworte:	ACIDE GRAS ACIDOS GRASOS ACTIVIDAD ENZIMATICA ACTIVITE ENZYMATIQUE Animals Biological and medical sciences Biotin - administration & dosage Biotin - deficiency BIOTINA BIOTINE Carboxylic Ester Hydrolases - metabolism CARENCE EN VITAMINES DEFICIENCIA DE VITAMINAS DIETA Fatty Acids - metabolism LIASAS LYASE Medical sciences Metabolic diseases Other nutritional diseases (malnutrition, nutritional and vitamin deficiencies...) PEAU PIEL (ANIMAL) RAT RATA Rats Rats, Inbred Strains REGIME ALIMENTAIRE Skin - enzymology Skin - metabolism Skin - pathology
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