A neuroattenuated ICP34.5-deficient herpes simplex virus type 1 replicates in ependymal cells of the murine central nervous system

S Kesari, TM Lasner, KR Balsara, BP Randazzo, VM Lee, JQ Trojanowski and NW Fraser The Wistar Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA. Herpes simplex virus type 1 (HSV-1) variant 1716 is deleted in the gene en...

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Veröffentlicht in:	Journal of general virology 1998-03, Vol.79 (3), p.525-536
Hauptverfasser:	Kesari, S, Lasner, TM, Balsara, KR, Randazzo, BP, Lee, VM, Trojanowski, JQ, Fraser, NW
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Brain - pathology Brain - virology Disease Susceptibility Ependyma - metabolism Ependyma - pathology Ependyma - virology Fluorescent Antibody Technique, Indirect Glial Fibrillary Acidic Protein - metabolism Herpes simplex virus Herpesvirus 1, Human - genetics Herpesvirus 1, Human - pathogenicity Herpesvirus 1, Human - physiology Immunohistochemistry In Situ Hybridization Injections Injections, Intraventricular Mice Mice, Inbred BALB C Microtubule-Associated Proteins - metabolism Viral Proteins - genetics Viral Proteins - metabolism Virus Latency Virus Replication
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