Randomised trial of isoniazid versus rifampicin and pyrazinamide for prevention of tuberculosis in HIV-1 infection

Tuberculosis is a common complication of HIV-1 infection, especially in developing countries. Practical and effective chemoprophylaxis regimens for HIV-1-related tuberculosis are needed. Our aim was to test the efficacy of isoniazid versus rifampicin with pyrazinamide for prevention of tuberculosis...

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Veröffentlicht in:	The Lancet (British edition) 1998-03, Vol.351 (9105), p.786-792
Hauptverfasser:	Halsey, Neal A, Coberly, Jacqueline S, Desormeaux, Julio, Losikoff, Phyllis, Atkinson, Joan, Moulton, Lawrence H, Contave, Mireil, Johnson, Michael, Davis, Homer, Geiter, Lawrence, Johnson, Erica, Huebner, Robin, Boulos, Reginald, Chaisson, Richard E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS-Related Opportunistic Infections - epidemiology AIDS-Related Opportunistic Infections - prevention & control AIDS/HIV Antitubercular Agents - therapeutic use Bacterial diseases Bacterial endocarditis, myocarditis and pericarditis. Bacterial diseases of the aorta, limb vessels and lymphatic vessels Biological and medical sciences Developing countries Drug Administration Schedule Drug therapy Female Follow-Up Studies HIV HIV Infections - complications HIV-1 Human bacterial diseases Human immunodeficiency virus Humans Infectious diseases Isoniazid - therapeutic use LDCs Lymphocytes Male Medical sciences Prevention Preventive medicine Prospective Studies Pyrazinamide - therapeutic use Rifampin - therapeutic use Time Factors Tuberculosis Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - prevention & control
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