Elevated Circulating E-Selectin, Intercellular Adhesion Molecule 1, and von Willebrand Factor in Patients with Severe Infection

To investigate interactions between the endothelium and leukocytes in patients with sepsis, we measured soluble adhesion molecules (sE-selectin and sICAM-1), von Willebrand factor antigen (vWf:Ag), myeloperoxidase (MPO), and lactoferrin (Lacto-f) as plasma markers of endothelial and neutrophil activ...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1998-03, Vol.157 (3), p.776-784
Hauptverfasser:	KAYAL, SAMER, JAIS, JEAN-PHILIPPE, AGUINI, NADIA, CHAUDIERE, JEAN, LABROUSSE, JACQUES
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over APACHE Bacteremia - blood Bacteremia - physiopathology Bacterial diseases Bacterial sepsis Biological and medical sciences Biomarkers - blood E-Selectin - blood Endothelium, Vascular - physiology Female Follow-Up Studies Forecasting Human bacterial diseases Humans Infectious diseases Intercellular Adhesion Molecule-1 - blood Lactoferrin - blood Leukocytes - physiology Logistic Models Male Medical sciences Middle Aged Multiple Organ Failure - blood Multiple Organ Failure - physiopathology Neutrophil Activation - physiology Peroxidase - blood Prognosis Sensitivity and Specificity Sepsis - blood Sepsis - physiopathology Shock, Septic - blood Shock, Septic - physiopathology Survival Rate Treatment Outcome von Willebrand Factor - analysis
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