Effect of glutamate transporter on neuronal damage induced by photochemical thrombotic brain ischemia

TO study the effects of glutamate transporters on the pathogenesis of brain infarct, pharmacological and histological analyses were carried out on the thrombotic focal ischemic model. Expression of mRNA coding for the glutamate transporter GLAST increased significantly in the penumbra at 72 h follow...

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Veröffentlicht in:	Neuroreport 1998-02, Vol.9 (3), p.441-446
Hauptverfasser:	Yan, Yi-Ping, Yin, Ke-Jie, Sun, Feng-Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport System X-AG Animals ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - pharmacology Biological and medical sciences Biological Transport - physiology Cerebral Infarction - drug therapy Dose-Response Relationship, Drug Glial Fibrillary Acidic Protein - analysis Ischemic Attack, Transient - drug therapy Ischemic Attack, Transient - pathology Male Medical sciences Neurology Neurons - drug effects Neurons - pathology Photochemistry Rats Rats, Sprague-Dawley RNA, Messenger - biosynthesis Thrombosis - drug therapy Thrombosis - pathology Vascular diseases and vascular malformations of the nervous system
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