Ethanol and neuronal calcium channels

Ethanol and neuronal calcium channels

Ethanol alters voltage-dependent calcium channels and receptor-operated channels which transport calcium [e.g., the ion channels associated with N-methyl-D-aspartate (NMDA) receptors]. However, the question which still remains unanswered is whether these modifications have any physiological signific...

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Veröffentlicht in:Alcohol (Fayetteville, N.Y.) N.Y.), 1990-05, Vol.7 (3), p.233-236
Hauptverfasser: Leslie, Steven W., Brown, Laurie M., Dildy, Jo Ellen, Sims, Joanne S.
Format: Artikel
Sprache:eng
Schlagworte:
Alcoholism and acute alcohol poisoning
Animals
Biological and medical sciences
Calcium Channels - drug effects
Calcium Channels - metabolism
Ethanol - pharmacology
Humans
Medical sciences
Neurons - drug effects
Neurons - metabolism
Toxicology
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Zusammenfassung:Ethanol alters voltage-dependent calcium channels and receptor-operated channels which transport calcium [e.g., the ion channels associated with N-methyl-D-aspartate (NMDA) receptors]. However, the question which still remains unanswered is whether these modifications have any physiological significance. This review will focus on the effects of ethanol on various calcium-related parameters with an emphasis on the possible relevance to the behavioral effects elicited by ethanol.
ISSN:0741-8329
1873-6823
DOI:10.1016/0741-8329(90)90011-Z