Therapy of bacterial vaginosis
Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of childbearing age. The prevalence in the UK is between 10 and 15%. The principal symptom is an offensive fishy smell, accompanied by an increased vaginal discharge. When BV develops, the concentrations of many a...
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| Veröffentlicht in: | Journal of antimicrobial chemotherapy 1998, Vol.41 (1), p.6-9 |
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| creator | HAY, P. E |
| description | Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of childbearing age. The prevalence in the UK is between 10 and 15%. The principal symptom is an offensive fishy smell, accompanied by an increased vaginal discharge. When BV develops, the concentrations of many anaerobic or facultative anaerobic species, including Gardnerella vaginalis, Bacteroides spp. and Mycoplasma hominis, increase up to a thousand-fold, overwhelming the usually dominant lactobacilli. In the most severe forms of BV the lactobacilli disappear. The bacteria adhere to desquamated squamated squamous epithelial cells, giving them the appearance of 'clue cells'. The pH of vaginal fluid increases from the normal, |
| doi_str_mv | 10.1093/jac/41.1.6 |
| format | Article |
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Some clinicians use alternative terms such as anaerobic vaginosis, non-specific vaginosis or even 'gardnerella'.</description><identifier>ISSN: 0305-7453</identifier><identifier>EISSN: 1460-2091</identifier><identifier>DOI: 10.1093/jac/41.1.6</identifier><identifier>PMID: 9511031</identifier><identifier>CODEN: JACHDX</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antifungal agents ; Antitrichomonal Agents - administration & dosage ; Bacteroides ; Bacteroides Infections - therapy ; Biological and medical sciences ; Clindamycin - administration & dosage ; Drug Therapy, Combination - therapeutic use ; Erythromycin - administration & dosage ; Female ; Gardnerella vaginalis ; Humans ; Medical sciences ; Metronidazole - administration & dosage ; Mycoplasma hominis ; Mycoplasma Infections - therapy ; Pharmacology. Drug treatments ; Pregnancy ; Pregnancy Complications ; Sexually Transmitted Diseases - drug therapy ; Vaginosis, Bacterial - drug therapy ; Vaginosis, Bacterial - therapy</subject><ispartof>Journal of antimicrobial chemotherapy, 1998, Vol.41 (1), p.6-9</ispartof><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-f8538551d72c51397bc6c207fdf8da5a62efe4fb640f075c9f9a48b3fe227b9f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2144737$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9511031$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HAY, P. E</creatorcontrib><title>Therapy of bacterial vaginosis</title><title>Journal of antimicrobial chemotherapy</title><addtitle>J Antimicrob Chemother</addtitle><description>Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of childbearing age. The prevalence in the UK is between 10 and 15%. The principal symptom is an offensive fishy smell, accompanied by an increased vaginal discharge. When BV develops, the concentrations of many anaerobic or facultative anaerobic species, including Gardnerella vaginalis, Bacteroides spp. and Mycoplasma hominis, increase up to a thousand-fold, overwhelming the usually dominant lactobacilli. In the most severe forms of BV the lactobacilli disappear. The bacteria adhere to desquamated squamated squamous epithelial cells, giving them the appearance of 'clue cells'. The pH of vaginal fluid increases from the normal, <4.5, to as high as 7.0. The term bacterial vaginosis was adopted in 1983, the word 'bacterial' to indicate that many bacterial species are present, and the suffix -'osis' because inflammation is absent. Some clinicians use alternative terms such as anaerobic vaginosis, non-specific vaginosis or even 'gardnerella'.</description><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antifungal agents</subject><subject>Antitrichomonal Agents - administration & dosage</subject><subject>Bacteroides</subject><subject>Bacteroides Infections - therapy</subject><subject>Biological and medical sciences</subject><subject>Clindamycin - administration & dosage</subject><subject>Drug Therapy, Combination - therapeutic use</subject><subject>Erythromycin - administration & dosage</subject><subject>Female</subject><subject>Gardnerella vaginalis</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Metronidazole - administration & dosage</subject><subject>Mycoplasma hominis</subject><subject>Mycoplasma Infections - therapy</subject><subject>Pharmacology. Drug treatments</subject><subject>Pregnancy</subject><subject>Pregnancy Complications</subject><subject>Sexually Transmitted Diseases - drug therapy</subject><subject>Vaginosis, Bacterial - drug therapy</subject><subject>Vaginosis, Bacterial - therapy</subject><issn>0305-7453</issn><issn>1460-2091</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0DtLA0EUBeBBlBijjb2SQiyETe6d95QSfEHAJtbD7OyMbthk40wi5N-7kiWt1SnOxykOIdcIEwTDpkvnpxwnOJEnZIhcQkHB4CkZAgNRKC7YObnIeQkAUkg9IAMjEIHhkNwuvkJym_24jePS-W1ItWvGP-6zXre5zpfkLLomh6s-R-Tj-Wkxey3m7y9vs8d54ZnS2yJqwbQQWCnqBTKjSi89BRWrqCsnnKQhBh5LySGCEt5E47guWQyUqtJENiL3h91Nar93IW_tqs4-NI1bh3aXrTKKaWnYvxAlV5widvDhAH1qc04h2k2qVy7tLYL9e812r1mOFq3s8E2_uitXoTrS_qauv-t7l71rYnJrX-cjo8i5Yor9AtyOctc</recordid><startdate>1998</startdate><enddate>1998</enddate><creator>HAY, P. E</creator><general>Oxford University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>1998</creationdate><title>Therapy of bacterial vaginosis</title><author>HAY, P. E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-f8538551d72c51397bc6c207fdf8da5a62efe4fb640f075c9f9a48b3fe227b9f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Antifungal agents</topic><topic>Antitrichomonal Agents - administration & dosage</topic><topic>Bacteroides</topic><topic>Bacteroides Infections - therapy</topic><topic>Biological and medical sciences</topic><topic>Clindamycin - administration & dosage</topic><topic>Drug Therapy, Combination - therapeutic use</topic><topic>Erythromycin - administration & dosage</topic><topic>Female</topic><topic>Gardnerella vaginalis</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Metronidazole - administration & dosage</topic><topic>Mycoplasma hominis</topic><topic>Mycoplasma Infections - therapy</topic><topic>Pharmacology. Drug treatments</topic><topic>Pregnancy</topic><topic>Pregnancy Complications</topic><topic>Sexually Transmitted Diseases - drug therapy</topic><topic>Vaginosis, Bacterial - drug therapy</topic><topic>Vaginosis, Bacterial - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HAY, P. E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of antimicrobial chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HAY, P. E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Therapy of bacterial vaginosis</atitle><jtitle>Journal of antimicrobial chemotherapy</jtitle><addtitle>J Antimicrob Chemother</addtitle><date>1998</date><risdate>1998</risdate><volume>41</volume><issue>1</issue><spage>6</spage><epage>9</epage><pages>6-9</pages><issn>0305-7453</issn><eissn>1460-2091</eissn><coden>JACHDX</coden><abstract>Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of childbearing age. The prevalence in the UK is between 10 and 15%. The principal symptom is an offensive fishy smell, accompanied by an increased vaginal discharge. When BV develops, the concentrations of many anaerobic or facultative anaerobic species, including Gardnerella vaginalis, Bacteroides spp. and Mycoplasma hominis, increase up to a thousand-fold, overwhelming the usually dominant lactobacilli. In the most severe forms of BV the lactobacilli disappear. The bacteria adhere to desquamated squamated squamous epithelial cells, giving them the appearance of 'clue cells'. The pH of vaginal fluid increases from the normal, <4.5, to as high as 7.0. The term bacterial vaginosis was adopted in 1983, the word 'bacterial' to indicate that many bacterial species are present, and the suffix -'osis' because inflammation is absent. Some clinicians use alternative terms such as anaerobic vaginosis, non-specific vaginosis or even 'gardnerella'.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>9511031</pmid><doi>10.1093/jac/41.1.6</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of antimicrobial chemotherapy, 1998, Vol.41 (1), p.6-9 |
| issn | 0305-7453 1460-2091 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antitrichomonal Agents - administration & dosage Bacteroides Bacteroides Infections - therapy Biological and medical sciences Clindamycin - administration & dosage Drug Therapy, Combination - therapeutic use Erythromycin - administration & dosage Female Gardnerella vaginalis Humans Medical sciences Metronidazole - administration & dosage Mycoplasma hominis Mycoplasma Infections - therapy Pharmacology. Drug treatments Pregnancy Pregnancy Complications Sexually Transmitted Diseases - drug therapy Vaginosis, Bacterial - drug therapy Vaginosis, Bacterial - therapy |
| title | Therapy of bacterial vaginosis |
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