Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study
The angioplasty substudy of the GUSTO IIb trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (MI). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who u...
Gespeichert in:
| Veröffentlicht in: | Cleveland Clinic journal of medicine 1998-02, Vol.65 (2), p.75-81 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 81 |
|---|---|
| container_issue | 2 |
| container_start_page | 75 |
| container_title | Cleveland Clinic journal of medicine |
| container_volume | 65 |
| creator | Brener, S J |
| description | The angioplasty substudy of the GUSTO IIb trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (MI). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who underwent primary angioplasty either died or suffered a disabling stroke or another myocardial infarction within 30 days, compared with 13.7% of patients who received fibrinolytic therapy, for an odds ratio of 0.67 (P = .033). This difference was less than in previous studies, possibly in part because fibrinolytic therapy has improved. The findings underscore the importance of promptly restoring complete, brisk, antegrade flow in the infarct-related artery, regardless of what treatment is used. |
| doi_str_mv | 10.3949/ccjm.65.2.75 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79734306</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79734306</sourcerecordid><originalsourceid>FETCH-LOGICAL-c243t-5a3f9fd949f963bd69ffec6b548870f398bbfec04b19a7c7b710cef9e9291c733</originalsourceid><addsrcrecordid>eNo9kMFLwzAchYMoc05vXoWcPNmaNE3S30FkDJ2FyQ5u59CkiXa060zaQ_97OzY8PXh8PB4fQveUxAxSeDZm18SCx0ks-QWaUmAQJZmASzQlGdCIUk6u0U0IO0ISThOYoAlwAgKyKXqZ77-r9lAXoRtw67GrtK_2bT2EKmA3FoXpO4s_81e8-bF4uf3arHGeaxy6vhxu0ZUr6mDvzjlD2_e3zeIjWq2X-WK-ikySsi7iBXPgyvGsA8F0KcA5a4TmaZZJ4hhkWo8FSTWFQhqpJSXGOrCQADWSsRl6PO0efPvb29CppgrG1nWxt20flATJUkbECD6dQOPbELx16uCrpvCDokQdbamjLSW4SpTkI_5w3u11Y8t_-KyH_QF3M2U-</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79734306</pqid></control><display><type>article</type><title>Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study</title><source>MEDLINE</source><source>EZB Electronic Journals Library</source><creator>Brener, S J</creator><creatorcontrib>Brener, S J</creatorcontrib><description>The angioplasty substudy of the GUSTO IIb trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (MI). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who underwent primary angioplasty either died or suffered a disabling stroke or another myocardial infarction within 30 days, compared with 13.7% of patients who received fibrinolytic therapy, for an odds ratio of 0.67 (P = .033). This difference was less than in previous studies, possibly in part because fibrinolytic therapy has improved. The findings underscore the importance of promptly restoring complete, brisk, antegrade flow in the infarct-related artery, regardless of what treatment is used.</description><identifier>ISSN: 0891-1150</identifier><identifier>EISSN: 1939-2869</identifier><identifier>DOI: 10.3949/ccjm.65.2.75</identifier><identifier>PMID: 9509698</identifier><language>eng</language><publisher>United States</publisher><subject>Angioplasty ; Fibrinolytic Agents - therapeutic use ; Humans ; Myocardial Infarction - drug therapy ; Myocardial Infarction - mortality ; Myocardial Infarction - surgery ; Randomized Controlled Trials as Topic ; Survival Rate ; Thrombolytic Therapy ; Treatment Outcome</subject><ispartof>Cleveland Clinic journal of medicine, 1998-02, Vol.65 (2), p.75-81</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9509698$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brener, S J</creatorcontrib><title>Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study</title><title>Cleveland Clinic journal of medicine</title><addtitle>Cleve Clin J Med</addtitle><description>The angioplasty substudy of the GUSTO IIb trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (MI). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who underwent primary angioplasty either died or suffered a disabling stroke or another myocardial infarction within 30 days, compared with 13.7% of patients who received fibrinolytic therapy, for an odds ratio of 0.67 (P = .033). This difference was less than in previous studies, possibly in part because fibrinolytic therapy has improved. The findings underscore the importance of promptly restoring complete, brisk, antegrade flow in the infarct-related artery, regardless of what treatment is used.</description><subject>Angioplasty</subject><subject>Fibrinolytic Agents - therapeutic use</subject><subject>Humans</subject><subject>Myocardial Infarction - drug therapy</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - surgery</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Survival Rate</subject><subject>Thrombolytic Therapy</subject><subject>Treatment Outcome</subject><issn>0891-1150</issn><issn>1939-2869</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMFLwzAchYMoc05vXoWcPNmaNE3S30FkDJ2FyQ5u59CkiXa060zaQ_97OzY8PXh8PB4fQveUxAxSeDZm18SCx0ks-QWaUmAQJZmASzQlGdCIUk6u0U0IO0ISThOYoAlwAgKyKXqZ77-r9lAXoRtw67GrtK_2bT2EKmA3FoXpO4s_81e8-bF4uf3arHGeaxy6vhxu0ZUr6mDvzjlD2_e3zeIjWq2X-WK-ikySsi7iBXPgyvGsA8F0KcA5a4TmaZZJ4hhkWo8FSTWFQhqpJSXGOrCQADWSsRl6PO0efPvb29CppgrG1nWxt20flATJUkbECD6dQOPbELx16uCrpvCDokQdbamjLSW4SpTkI_5w3u11Y8t_-KyH_QF3M2U-</recordid><startdate>19980201</startdate><enddate>19980201</enddate><creator>Brener, S J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19980201</creationdate><title>Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study</title><author>Brener, S J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c243t-5a3f9fd949f963bd69ffec6b548870f398bbfec04b19a7c7b710cef9e9291c733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Angioplasty</topic><topic>Fibrinolytic Agents - therapeutic use</topic><topic>Humans</topic><topic>Myocardial Infarction - drug therapy</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - surgery</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Survival Rate</topic><topic>Thrombolytic Therapy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brener, S J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cleveland Clinic journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brener, S J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study</atitle><jtitle>Cleveland Clinic journal of medicine</jtitle><addtitle>Cleve Clin J Med</addtitle><date>1998-02-01</date><risdate>1998</risdate><volume>65</volume><issue>2</issue><spage>75</spage><epage>81</epage><pages>75-81</pages><issn>0891-1150</issn><eissn>1939-2869</eissn><abstract>The angioplasty substudy of the GUSTO IIb trial confirmed that the short-term results of primary angioplasty are better than those of fibrinolytic therapy in patients with acute myocardial infarction (MI). In the largest and most rigorous study of this topic performed to date, 9.6% of patients who underwent primary angioplasty either died or suffered a disabling stroke or another myocardial infarction within 30 days, compared with 13.7% of patients who received fibrinolytic therapy, for an odds ratio of 0.67 (P = .033). This difference was less than in previous studies, possibly in part because fibrinolytic therapy has improved. The findings underscore the importance of promptly restoring complete, brisk, antegrade flow in the infarct-related artery, regardless of what treatment is used.</abstract><cop>United States</cop><pmid>9509698</pmid><doi>10.3949/ccjm.65.2.75</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0891-1150 |
| ispartof | Cleveland Clinic journal of medicine, 1998-02, Vol.65 (2), p.75-81 |
| issn | 0891-1150 1939-2869 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79734306 |
| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Angioplasty Fibrinolytic Agents - therapeutic use Humans Myocardial Infarction - drug therapy Myocardial Infarction - mortality Myocardial Infarction - surgery Randomized Controlled Trials as Topic Survival Rate Thrombolytic Therapy Treatment Outcome |
| title | Angioplasty or fibrinolysis for acute MI? The GUSTO IIb study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T19%3A48%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Angioplasty%20or%20fibrinolysis%20for%20acute%20MI?%20The%20GUSTO%20IIb%20study&rft.jtitle=Cleveland%20Clinic%20journal%20of%20medicine&rft.au=Brener,%20S%20J&rft.date=1998-02-01&rft.volume=65&rft.issue=2&rft.spage=75&rft.epage=81&rft.pages=75-81&rft.issn=0891-1150&rft.eissn=1939-2869&rft_id=info:doi/10.3949/ccjm.65.2.75&rft_dat=%3Cproquest_cross%3E79734306%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79734306&rft_id=info:pmid/9509698&rfr_iscdi=true |