Generation of a Monoclonal Antibody That Induces Apoptosis of Hematopoietic Cells

Here, we developed anti-murine myeloid cell (NFS-60 cell) monoclonal antibodies in order to characterize the further mechanism of cell-to-cell interaction between the stromal cells and the hematopoietic progenitor cells. The established antibody, designated mAb UNF, inhibited proliferation of NFS-60...

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Veröffentlicht in:	Biochemical and biophysical research communications 1998-02, Vol.243 (3), p.727-731
Hauptverfasser:	Mio, Hiroyuki, Satoh, Mitsuo, Yokokawa, Sachiko, Nishio, Hitoshi, Suda, Toshio, Tamaoki, Tatsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - pharmacology Antigens - analysis Antigens - immunology Apoptosis Bone Marrow Cells - immunology Cell Aggregation - drug effects Cell Communication Cell Division - drug effects Cycloheximide - pharmacology Flow Cytometry Fluorescent Antibody Technique, Indirect Glycolipids - immunology hematopoietic stem cells Hematopoietic Stem Cells - physiology Leukemia, Myeloid - immunology Leukemia, Myeloid - pathology Mice monoclonal antibody Protein Synthesis Inhibitors - pharmacology Stromal Cells - physiology Tumor Cells, Cultured
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