CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells

We examined the functional properties of CK beta-11/MIP-3 beta/ELC, a recently reported CC chemokine that specifically binds to a chemokine receptor, EBI1/BLR2/CCR7. CK beta-11/MIP-3 beta/ELC is distantly related to other CC and CXC chemokines in primary amino acid sequence structure. Recombinant hu...

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Veröffentlicht in:	The Journal of immunology (1950) 1998-03, Vol.160 (5), p.2418-2424
Hauptverfasser:	Kim, C H, Pelus, L M, White, J R, Applebaum, E, Johanson, K, Broxmeyer, H E
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals B-Lymphocytes - metabolism B-Lymphocytes - physiology Calcium - metabolism Chemokine CCL19 Chemokines - physiology Chemokines, CC Chemotaxis, Leukocyte - drug effects Chemotaxis, Leukocyte - immunology Granulocytes - physiology Humans Ligands Macrophage Inflammatory Proteins - physiology Mice Monocytes - physiology Pertussis Toxin Polymers - metabolism Receptors, CCR7 Receptors, Cell Surface - physiology Receptors, Chemokine Spleen - cytology T-Lymphocytes - metabolism T-Lymphocytes - physiology Virulence Factors, Bordetella - pharmacology
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