Stimulation of Human T Lymphocytes Obtained from Toxoplasma gondii-Seronegative Persons by Proteins Derived from T. gondii

Toxoplasma gondii antigens are superantigens in mice. To investigate a superantigen effect in humans, lymphocytes from T. gondii-seronegative subjects were studied for proliferation to T. gondii antigens (TA). Marked cellular proliferation, predominantly of CD4+ lymphocytes, was apparent. TA elicite...

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Veröffentlicht in:	The Journal of infectious diseases 1998-03, Vol.177 (3), p.746-753
Hauptverfasser:	Purner, Matthew B., Berens, Randolph L., Tomavo, Stanislas, Lecordier, Laurece, Cesbron-Delauw, Marie-France, Kotzin, Brian L., Curiel, Tyler J.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Antigen-Presenting Cells - immunology Antigens Antigens, Protozoan - immunology Biological and medical sciences CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Cell growth Cord blood Cytotoxicity, Immunologic Fetal Blood - cytology Fetal Blood - immunology Human protozoal diseases Humans Infections Infectious diseases Lymphocyte Activation Lymphocytes Major Articles Medical sciences Parasitic diseases Proteins Protozoal diseases Receptors Receptors, Antigen, T-Cell, alpha-beta Serologic Tests Superantigens Superantigens - immunology T lymphocytes T-Lymphocyte Subsets - immunology T-Lymphocytes - immunology Toxoplasma - immunology Toxoplasmosis Vaccination
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