Blood-nerve barrier in IgM paraproteinemic neuropathy : a clinicopathologic assessment

We report the pathologic findings in a patient with sensorimotor neuropathy associated with Waldenström's macroglobulinemia, particularly in relation to blood-nerve barrier defects. The monoclonal IgM was of kappa type and possessed anti-HNK-1 activity. A sural nerve biopsy specimen revealed se...

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Veröffentlicht in:	Acta neuropathologica 1998-02, Vol.95 (2), p.184-192
Hauptverfasser:	KANDA, T, USUI, S, BEPPU, H, MIYAMOTO, K, YAMAWAKI, M, ODA, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Autopsy Biological and medical sciences Biopsy Central nervous system Endothelial cells Endothelium, Vascular - pathology Endothelium, Vascular - ultrastructure Female Fibers Hematologic and hematopoietic diseases Humans Immunoglobulin M Immunoglobulin M - blood Immunoglobulin M - cerebrospinal fluid Intercellular Junctions - pathology Intercellular Junctions - ultrastructure Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocytes B Macroglobulinemia Male Medical sciences Microscopy, Electron Middle Aged Nerve Fibers - pathology Nerve Fibers - ultrastructure Nervous system Peripheral nerves Peripheral neuropathy Reference Values Sensorimotor system Spinal Cord - pathology Spinal Nerve Roots - pathology Sural nerve Sural Nerve - blood supply Sural Nerve - pathology Sural Nerve - ultrastructure Waldenstrom Macroglobulinemia - immunology Waldenstrom Macroglobulinemia - pathology
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