Failure of Zidovudine Prophylaxis after Accidental Exposure to HIV-1

ON the basis of encouraging data from two studies in animals, 1 , 2 the manufacturer of the antiretroviral nucleoside analogue zidovudine (formerly azido--thymidine [AZT]) has initiated a placebo-controlled trial to assess the chemoprophylactic efficacy of zidovudine after occupational or nosocomial...

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Veröffentlicht in:	The New England journal of medicine 1990-05, Vol.322 (19), p.1375-1377
Hauptverfasser:	Lange, Joep M.A, Boucher, Charles A.B, Hollar, Carla E.M, Wiltink, Ed H.H, Reiss, Peter, van Royen, Eric A, Roos, Marijke, Danner, Sven A, Goudsmit, Jaap
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS AIDS/HIV Biological and medical sciences Drugs Health care HIV Infections - prevention & control HIV Infections - transmission Humans Iatrogenic Disease Immunopathology Male Medical research Medical sciences Middle Aged Time Factors Transfusion Reaction Zidovudine - therapeutic use
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