Cyclin-dependent Kinase Inhibitor p16INK4A Inhibits Phosphorylation of RNA Polymerase II by General Transcription Factor TFIIH

The cell cycle is regulated by various protein kinases, including cyclin-dependent kinases (CDKs). D-type CDKs, CDK4, and CDK6, phosphorylate retinoblastoma protein and are believed to regulate through the G1 phase of the cell cycle. CDK inhibitor p16INK4A has been characterized as binding CDK4 and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 1998-03, Vol.273 (10), p.5427-5430
1. Verfasser:	Serizawa, Hiroaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Cyclin-Dependent Kinase Inhibitor p16 - metabolism Cyclin-Dependent Kinase Inhibitor p16 - pharmacology Cyclin-Dependent Kinases G1 Phase - physiology Gene Expression Regulation - genetics Phosphorylation Protein Kinase Inhibitors Protein-Serine-Threonine Kinases - metabolism Recombinant Proteins - genetics RNA Polymerase II - antagonists & inhibitors RNA Polymerase II - metabolism Thymus Gland - chemistry Transcription Factor TFIIH Transcription Factors - antagonists & inhibitors Transcription Factors, TFII Transcription, Genetic - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!