Age-associated decrease in response of rat aquaporin-2 gene expression to dehydration

It is well known that urine-concentrating ability decreases with aging and that this decreasing ability results from a reduced sensitivity of the renal collecting duct to arginine vasopressin (AVP). AVP regulates the water channel (aquaporin-2: AQP2) through V2 receptors and increases the water perm...

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Veröffentlicht in:	Life sciences (1973) 1998, Vol.62 (10), p.873-882
Hauptverfasser:	Terashima, Yasuhiro, Kondo, Kunikazu, Inagaki, Akemi, Yokoi, Hisashi, Arima, Hiroshi, Murase, Takashi, Iwasaki, Yasumasa, Oiso, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	aging Aging - genetics Animals Aquaporin 2 Aquaporin 6 Aquaporins Dehydration - genetics Gene Expression Regulation - physiology Ion Channels - genetics mRNA Rats urine-concentration ability vasopressin V2 receptor
Online-Zugang:	Volltext
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