Carotid body dopaminergic mechanisms are functional after acclimatization to hypoxia in goats

Ventilatory acclimatization to sustained hypoxia (VASH) is the time-dependent increase in ventilation that occurs during prolonged exposure to hypoxia. We tested the hypothesis that carotid body (CB) dopaminergic mechanisms are down-regulated during VASH, which would allow CB afferent discharge and...

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Veröffentlicht in:	Respiration physiology 1998, Vol.111 (1), p.25-32
Hauptverfasser:	Janssen, P.L., O'Halloran, K.D., Pizarro, J., Dwinell, M.R., Bisgard, G.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization - physiology Animals Carotid Body - physiology Carotid body, sustained hypoxia, dopamine Chemoreceptor Cells - drug effects Chemoreceptor Cells - physiology Control of breathing, sustained hypoxia, carotid body Domperidone - pharmacology Female Goats Hypoxia - physiopathology Hypoxia, sustained, ventilatory acclimatization, carotid body Male Mammals, goat Mediators, dopamine Pharmacological agents, domperidone Pulmonary Ventilation - physiology Receptors, Dopamine D2 - drug effects Receptors, Dopamine D2 - physiology
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