Conservation of locus-specific microsatellite variability across species: a comparison of two Drosophila sibling species, D. melanogaster and D. simulans

Conservation of locus-specific microsatellite variability across species: a comparison of two Drosophila sibling species, D. melanogaster and D. simulans

Fifteen microsatellite loci were studied in Drosophila melanogaster and Drosophila simulans, two closely related sibling species which split 2-3.5 MYA. Within-species variances in repeat number were found to differ up to 1,000-fold among individual microsatellite loci. A significant correlation of l...

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Veröffentlicht in:Molecular biology and evolution 1998-02, Vol.15 (2), p.176-184
Hauptverfasser: Harr, B, Zangerl, B, Brem, G, Schlötterer, C
Format: Artikel
Sprache:eng
Schlagworte:
Africa
Animals
Drosophila - classification
Drosophila - genetics
Drosophila melanogaster - classification
Drosophila melanogaster - genetics
Evolution, Molecular
Genetic Markers
Microsatellite Repeats
Phylogeny
Polymerase Chain Reaction
Species Specificity
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container_title Molecular biology and evolution
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creator Harr, B
Zangerl, B
Brem, G
Schlötterer, C
description Fifteen microsatellite loci were studied in Drosophila melanogaster and Drosophila simulans, two closely related sibling species which split 2-3.5 MYA. Within-species variances in repeat number were found to differ up to 1,000-fold among individual microsatellite loci. A significant correlation of log variances between both species indicated a locus-specific mutation rate of microsatellites. Hence, locus-specific effects are apparently among the major forces influencing microsatellite variation and deserve more consideration in microsatellite analysis.
doi_str_mv 10.1093/oxfordjournals.molbev.a025913
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subjects Africa
Animals
Drosophila - classification
Drosophila - genetics
Drosophila melanogaster - classification
Drosophila melanogaster - genetics
Evolution, Molecular
Genetic Markers
Microsatellite Repeats
Phylogeny
Polymerase Chain Reaction
Species Specificity
title Conservation of locus-specific microsatellite variability across species: a comparison of two Drosophila sibling species, D. melanogaster and D. simulans
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