Detection of Antibodies in Late Lyme Disease
As the geographic distribution and variety of atypical presentations of Lyme disease have become more fully appreciated, the clinician has become more dependent on serologic information to identify patients with Lyme disease. Unfortunately, when these tests are used in areas of sporadic occurrence o...
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| Veröffentlicht in: | Journal of Infectious Diseases 1990-05, Vol.161 (5), p.1034-1035 |
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| container_end_page | 1035 |
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| container_issue | 5 |
| container_start_page | 1034 |
| container_title | Journal of Infectious Diseases |
| container_volume | 161 |
| creator | Nelson, Jeffrey A. Bankowski, Matthew J. Newton, Barbara J. Benson, Constance A. Kaplan, Raymond Landau, William Trenholme, Gordon M. Peeples, Mark E. |
| description | As the geographic distribution and variety of atypical presentations of Lyme disease have become more fully appreciated, the clinician has become more dependent on serologic information to identify patients with Lyme disease. Unfortunately, when these tests are used in areas of sporadic occurrence of Lyme disease and with atypical clinical syndromes, the likelihood of false-positive results increases. In addition to the expanded use of available assays, there has been a rapid increase in the variety of commercial and research methods used to detect antibodies to Borrelia burgdorferi . We evaluated the consistency of results among several of these methods when used with a population from northeastern Illinois. |
| doi_str_mv | 10.1093/infdis/161.5.1034 |
| format | Article |
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Unfortunately, when these tests are used in areas of sporadic occurrence of Lyme disease and with atypical clinical syndromes, the likelihood of false-positive results increases. In addition to the expanded use of available assays, there has been a rapid increase in the variety of commercial and research methods used to detect antibodies to Borrelia burgdorferi . We evaluated the consistency of results among several of these methods when used with a population from northeastern Illinois.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6591</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/161.5.1034</identifier><identifier>PMID: 2324533</identifier><identifier>CODEN: JIDIAQ</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Antibodies ; Antibodies, Bacterial - analysis ; Antigens ; Bacteriological methods and techniques used in bacteriology ; Bacteriology ; Biological and medical sciences ; Borrelia burgdorferi Group - immunology ; Cellulose nitrate ; Correspondence ; Enzyme linked immunosorbent assay ; Epidemiology ; Exanthema ; Fundamental and applied biological sciences. 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Unfortunately, when these tests are used in areas of sporadic occurrence of Lyme disease and with atypical clinical syndromes, the likelihood of false-positive results increases. In addition to the expanded use of available assays, there has been a rapid increase in the variety of commercial and research methods used to detect antibodies to Borrelia burgdorferi . We evaluated the consistency of results among several of these methods when used with a population from northeastern Illinois.</description><subject>Antibodies</subject><subject>Antibodies, Bacterial - analysis</subject><subject>Antigens</subject><subject>Bacteriological methods and techniques used in bacteriology</subject><subject>Bacteriology</subject><subject>Biological and medical sciences</subject><subject>Borrelia burgdorferi Group - immunology</subject><subject>Cellulose nitrate</subject><subject>Correspondence</subject><subject>Enzyme linked immunosorbent assay</subject><subject>Epidemiology</subject><subject>Exanthema</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Lyme disease</subject><subject>Lyme Disease - diagnosis</subject><subject>Microbiology</subject><subject>Pseudomonas aeruginosa</subject><subject>Virulence</subject><issn>0022-1899</issn><issn>1537-6591</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAURi0EglL4AQxIGRATKb6-uXE8Ih4tUiSGgkAslus4kiEPiFMJ_j2pWsrIZMnnu2c4jJ0AnwBXeOmbsvDhElKY0PCDyQ4bAaGMU1Kwy0acCxFDptQBOwzhjXOAjNM-2xcoEkIcsYsb1zvb-7aJ2jK6anq_aAvvQuSbKDe9i_Lv2kU3PjgT3BHbK00V3PHmHbOnu9vH61mcP0zvr6_y2Cak-lhZsiTQcDAqNaAckC0wFZgJWUJZIFglUwC7AORSGYuJKhI0ClInUrA4Zudr70fXfi5d6HXtg3VVZRrXLoOWSgKpDP4dAkmZUZYNQ1gPbdeG0LlSf3S-Nt23Bq5XKfU6pR5SatKrlMPN6Ua-XNSu2F5s2g38bMNNsKYqO9PYwfA7I0IFgH-at9C33RYjh8Ej5MDjNfehd19bbrp3nUqUpGcvrzqbT-dA05l-xh9RF5Lw</recordid><startdate>19900501</startdate><enddate>19900501</enddate><creator>Nelson, Jeffrey A.</creator><creator>Bankowski, Matthew J.</creator><creator>Newton, Barbara J.</creator><creator>Benson, Constance A.</creator><creator>Kaplan, Raymond</creator><creator>Landau, William</creator><creator>Trenholme, Gordon M.</creator><creator>Peeples, Mark E.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>19900501</creationdate><title>Detection of Antibodies in Late Lyme Disease</title><author>Nelson, Jeffrey A. ; Bankowski, Matthew J. ; Newton, Barbara J. ; Benson, Constance A. ; Kaplan, Raymond ; Landau, William ; Trenholme, Gordon M. ; Peeples, Mark E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-9c5c523a01a96a19e15cd3623827f1fd31c97611cb13079ac349d43a916e261c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Antibodies</topic><topic>Antibodies, Bacterial - analysis</topic><topic>Antigens</topic><topic>Bacteriological methods and techniques used in bacteriology</topic><topic>Bacteriology</topic><topic>Biological and medical sciences</topic><topic>Borrelia burgdorferi Group - immunology</topic><topic>Cellulose nitrate</topic><topic>Correspondence</topic><topic>Enzyme linked immunosorbent assay</topic><topic>Epidemiology</topic><topic>Exanthema</topic><topic>Fundamental and applied biological sciences. 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| identifier | ISSN: 0022-1899 |
| ispartof | Journal of Infectious Diseases, 1990-05, Vol.161 (5), p.1034-1035 |
| issn | 0022-1899 1537-6591 1537-6613 |
| language | eng |
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| source | MEDLINE; Jstor Complete Legacy |
| subjects | Antibodies Antibodies, Bacterial - analysis Antigens Bacteriological methods and techniques used in bacteriology Bacteriology Biological and medical sciences Borrelia burgdorferi Group - immunology Cellulose nitrate Correspondence Enzyme linked immunosorbent assay Epidemiology Exanthema Fundamental and applied biological sciences. Psychology Humans Lyme disease Lyme Disease - diagnosis Microbiology Pseudomonas aeruginosa Virulence |
| title | Detection of Antibodies in Late Lyme Disease |
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