Granuloma-Forming Activity and Antitumor Activity of Newly Isolated Mycoloyl Glycolipid from Rhodococcus terrae 70012 (Rt. GM-2)

A newly isolated mycoloyl glycolipid (Rt. GM-2) from Rhodococcus terrae 70012 was identified and the granulomagenic and antitumor activities were studied as compared with trehalose-6, 6'-dimycolate (cord factor) also from R. terrae (Rt. TDM). The alkaline hydrolysis products of Rt. GM-2 contain...

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Veröffentlicht in:	MICROBIOLOGY and IMMUNOLOGY 1990, Vol.34(1), pp.45-53
Hauptverfasser:	Natsuhara, Yayoi, Yoshinaga, Junji, Shogaki, Takeshi, Sumi-Nishikawa, Yukie, Kurano, Satoko, Kato, Yoshiko, Kaneda, Kenji, Oka, Shiro, Yano, Ikuya
Format:	Artikel
Sprache:	eng
Schlagworte:	6-O- alpha -mycoloyl 6'-O- beta -ketomycoloyl trehalose Adjuvants, Immunologic Animals Antineoplastic Agents - therapeutic use Cord Factors - therapeutic use Glycolipids - isolation & purification Glycolipids - therapeutic use granuloma Granuloma - immunology Male Mice Mice, Inbred BALB C Mycolic Acids - isolation & purification Mycolic Acids - therapeutic use mycoloyl glycolipids Organ Specificity Rhodococcus Rhodococcus - metabolism Sarcoma - drug therapy sarcoma 180 trehalose 6,6'-dimycolate Tumor Cells, Cultured
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