24-Homologated 1,25-dihydroxyvitamin D3 compounds: separation of calcium and cell differentiation activities

A series of 24-homologated 1,25-dihydroxyvitamin D3 compounds have been chemically synthesized and studied with regard to their activity in inducing differentiation of human promyelocyte HL-60 cells to monocytes and in calcium mobilizing activity in vitamin D deficient rats. Homologation of 1,25-dih...

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Veröffentlicht in:	Biochemistry (Easton) 1990-01, Vol.29 (1), p.190-196
Hauptverfasser:	Perlman, Kato, Kutner, Andrzej, Prahl, Jean, Smith, Connie, Inaba, Masaaki, Schnoes, Heinrich K, DeLuca, H. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Calcitriol - analogs & derivatives Calcitriol - metabolism Calcitriol - physiology Calcium - metabolism Cell Differentiation - physiology Coenzymes, vitamins Fundamental and applied biological sciences. Psychology Humans Intestinal Mucosa - metabolism Leukemia, Experimental - pathology Male Other biological molecules Rats Rats, Inbred Strains Structure-Activity Relationship Tumor Cells, Cultured
Online-Zugang:	Volltext
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