Improved local delivery of TGF-beta2 by binding to injectable fibrillar collagen via difunctional polyethylene glycol

To overcome rapid diffusion and clearance from the implant site and to increase stability, recombinant transforming growth factor beta2 (TGF-beta2) was covalently bound to injectable bovine dermal fibrillar collagen (FC) and its activity compared to admixed TGF-beta2. Covalent binding was achieved i...

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Veröffentlicht in:	Journal of biomedical materials research 1998-03, Vol.39 (4), p.539-548
Hauptverfasser:	Bentz, H, Schroeder, J A, Estridge, T D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cattle Cell Line Collagen - metabolism Male Mink Polyethylene Glycols Protein Binding Rats Solubility Transforming Growth Factor beta - administration & dosage Transforming Growth Factor beta - metabolism
Online-Zugang:	Volltext
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