Effects of [1-desamino-8-D-arginine]vasopressin and papaverine on rabbit renal pelvis
The effects of [1-desamino-8-D-arginine]vasopressin (DDAVP) (V 2 receptor agonist) and papaverine on four continuous circular smooth muscle strips in rabbit renal pelvis were studied by an isometric tension recording methods. DDAVP suppressed spontaneous contractions in a dose-dependent and region-d...
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| Veröffentlicht in: | European journal of pharmacology 1990-01, Vol.175 (3), p.359-362 |
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| container_title | European journal of pharmacology |
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| creator | Kimoto, Yasusuke Constantinou, Christos E. |
| description | The effects of [1-desamino-8-D-arginine]vasopressin (DDAVP) (V
2 receptor agonist) and papaverine on four continuous circular smooth muscle strips in rabbit renal pelvis were studied by an isometric tension recording methods. DDAVP suppressed spontaneous contractions in a dose-dependent and region-dependent way. Papaverine suppressed these contractions in a dose-dependent way simultaneously in all four portions. These results suggest that there may be distribution differences of V
2 receptors in the renal pelvis. Together with its anti-diuretic action, DDAVP may merit consideration for the treatment of renal colic. |
| doi_str_mv | 10.1016/0014-2999(90)90577-S |
| format | Article |
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2 receptor agonist) and papaverine on four continuous circular smooth muscle strips in rabbit renal pelvis were studied by an isometric tension recording methods. DDAVP suppressed spontaneous contractions in a dose-dependent and region-dependent way. Papaverine suppressed these contractions in a dose-dependent way simultaneously in all four portions. These results suggest that there may be distribution differences of V
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2 receptor agonist) and papaverine on four continuous circular smooth muscle strips in rabbit renal pelvis were studied by an isometric tension recording methods. DDAVP suppressed spontaneous contractions in a dose-dependent and region-dependent way. Papaverine suppressed these contractions in a dose-dependent way simultaneously in all four portions. These results suggest that there may be distribution differences of V
2 receptors in the renal pelvis. Together with its anti-diuretic action, DDAVP may merit consideration for the treatment of renal colic.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Deamino Arginine Vasopressin - pharmacology</subject><subject>In Vitro Techniques</subject><subject>Isometric Contraction</subject><subject>kidney</subject><subject>Kidney Pelvis - drug effects</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle Relaxation - drug effects</subject><subject>Muscle, Smooth - drug effects</subject><subject>papaverine</subject><subject>Papaverine - pharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Rabbits</subject><subject>smooth muscle</subject><subject>Urinary system</subject><issn>0014-2999</issn><issn>1879-0712</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcFq3DAQhkVoSbdJ3iAFH0ppD0pGsmxZl0JJ0zQQyCHNqQQhS-Oi4pVdze5C3z7a7rLHhjnM4f9mGH1i7FzAhQDRXgIIxaUx5qOBTwYarfnDEVuIThsOWshXbHFA3rC3RL8BoDGyOWbHspZ13cgFe7weBvQrqqah-il4QHLLmCbe8a_c5V8xxYRPG0fTnJEopsqlUM1udhvMJaqmVGXX93FVZUxurGYcN5FO2evBjYRn-37CHr9d_7j6zu_ub26vvtxxr9p6xbsWpWwg-NApKdoOlA5oBt_qXjVQblS9dsE0MoCXThndQqgNiLpHN4CA-oR92O2d8_RnjbSyy0gex9ElnNZktdHlxVC_CIpGaTCgC6h2oM8TUcbBzjkuXf5rBditdrt1ardOrQH7T7t9KGPv9vvX_RLDYWjvueTv97kj78Yhu-QjHbC2k6pUwT7vMCzSNhGzJR8xeQwxl1-yYYr_v-MZ36Wc6w</recordid><startdate>19900117</startdate><enddate>19900117</enddate><creator>Kimoto, Yasusuke</creator><creator>Constantinou, Christos E.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19900117</creationdate><title>Effects of [1-desamino-8-D-arginine]vasopressin and papaverine on rabbit renal pelvis</title><author>Kimoto, Yasusuke ; Constantinou, Christos E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c463t-86e2250dcd842168047de9fc67b4502324b7ad952d0c2a49760d39013beaf0103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Deamino Arginine Vasopressin - pharmacology</topic><topic>In Vitro Techniques</topic><topic>Isometric Contraction</topic><topic>kidney</topic><topic>Kidney Pelvis - drug effects</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscle Relaxation - drug effects</topic><topic>Muscle, Smooth - drug effects</topic><topic>papaverine</topic><topic>Papaverine - pharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Rabbits</topic><topic>smooth muscle</topic><topic>Urinary system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kimoto, Yasusuke</creatorcontrib><creatorcontrib>Constantinou, Christos E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kimoto, Yasusuke</au><au>Constantinou, Christos E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of [1-desamino-8-D-arginine]vasopressin and papaverine on rabbit renal pelvis</atitle><jtitle>European journal of pharmacology</jtitle><addtitle>Eur J Pharmacol</addtitle><date>1990-01-17</date><risdate>1990</risdate><volume>175</volume><issue>3</issue><spage>359</spage><epage>362</epage><pages>359-362</pages><issn>0014-2999</issn><eissn>1879-0712</eissn><coden>EJPHAZ</coden><abstract>The effects of [1-desamino-8-D-arginine]vasopressin (DDAVP) (V
2 receptor agonist) and papaverine on four continuous circular smooth muscle strips in rabbit renal pelvis were studied by an isometric tension recording methods. DDAVP suppressed spontaneous contractions in a dose-dependent and region-dependent way. Papaverine suppressed these contractions in a dose-dependent way simultaneously in all four portions. These results suggest that there may be distribution differences of V
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| identifier | ISSN: 0014-2999 |
| ispartof | European journal of pharmacology, 1990-01, Vol.175 (3), p.359-362 |
| issn | 0014-2999 1879-0712 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Biological and medical sciences Deamino Arginine Vasopressin - pharmacology In Vitro Techniques Isometric Contraction kidney Kidney Pelvis - drug effects Male Medical sciences Muscle Relaxation - drug effects Muscle, Smooth - drug effects papaverine Papaverine - pharmacology Pharmacology. Drug treatments Rabbits smooth muscle Urinary system |
| title | Effects of [1-desamino-8-D-arginine]vasopressin and papaverine on rabbit renal pelvis |
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