Physical and genetic mapping of the human X chromosome centromere: repression of recombination

Classical genetic studies in Drosophila and yeast have shown that chromosome centromeres have a cis-acting ability to repress meiotic exchange in adjacent DNA. To determine whether a similar phenomenon exists at human centromeres, we measured the rate of meiotic recombination across the centromere o...

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Veröffentlicht in:	Genome research 1998-02, Vol.8 (2), p.100-110
Hauptverfasser:	Mahtani, M M, Willard, H F
Format:	Artikel
Sprache:	eng
Schlagworte:	Centromere - genetics Centromere - metabolism Chromosome Mapping - methods Humans Meiosis - genetics Recombination, Genetic Restriction Mapping - methods X Chromosome - genetics X Chromosome - metabolism
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