Analysis of the early embryonic cell cycles of Xenopus; regulation of cell cycle length by Xe-wee1 and Mos

In Xenopus, cdc2 tyrosine phosphorylation is detected in the first 60–75 minute cell cycle but not in the next eleven cell cycles (cycles 2–12) which are only 30 minutes long. Here we report that the wee1/cdc25 ratio increases before the first mitotic interphase. We show that the Xe-wee1 protein...

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