New hepatitis B virus mutant form in a blood donor that is undetectable in several hepatitis B surface antigen screening assays

BACKGROUND: Envelope mutant forms of hepatitis B virus (HBV), impairing HBV antibody recognition, have been reported with mutations in single or multiple sites of the hepatitis B surface antigen (HBsAg) group‐ specific “a” determinant. Blood donors infected with such an HBsAg mutant form of HBV may...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 1998-01, Vol.38 (1), p.56-59
Hauptverfasser:	Jongerius, J.M., Wester, M., Cuypers, H. T.M, van Oostendorp, W.R., Lelie, P.N., van der Poel, C.L., van Leeuwen, E.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Blood Donors Female Hepatitis B - diagnosis Hepatitis B Surface Antigens - analysis Hepatitis B Surface Antigens - genetics Hepatitis B virus - genetics Hepatitis B virus - isolation & purification Human viral diseases Humans Immunoenzyme Techniques Infectious diseases Medical sciences Mutation Predictive Value of Tests Reagent Kits, Diagnostic Viral diseases Viral hepatitis Viremia - diagnosis
Online-Zugang:	Volltext
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