Heterogeneity and expression of the Plasmodium falciparum 5.8S ribosomal RNA genes
The number and expression of some of the large ribosomal RNA (rRNA) gene classes present in the human malaria parasite Plasmodium falciparum was determined. Southern blot analyses, using the 5.8S rRNA coding region as a marker, indicate that the P. falciparum genome contains at least 5 distinct subc...
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| Veröffentlicht in: | Molecular and biochemical parasitology 1990, Vol.38 (1), p.113-120 |
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| container_title | Molecular and biochemical parasitology |
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| creator | Shippen-Lentz, Dorothy Afroze, Talat Vezza, Anne Carmel |
| description | The number and expression of some of the large ribosomal RNA (rRNA) gene classes present in the human malaria parasite
Plasmodium falciparum was determined. Southern blot analyses, using the 5.8S rRNA coding region as a marker, indicate that the
P. falciparum genome contains at least 5 distinct subclasses of large rRNA genes. Dideoxy sequencing of the 5.8S rRNA domain and Northern blot analyses demonstrate that only one subclass is transcribed during the parasite's asexual erythrocyte life cycle. |
| doi_str_mv | 10.1016/0166-6851(90)90211-4 |
| format | Article |
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Plasmodium falciparum was determined. Southern blot analyses, using the 5.8S rRNA coding region as a marker, indicate that the
P. falciparum genome contains at least 5 distinct subclasses of large rRNA genes. Dideoxy sequencing of the 5.8S rRNA domain and Northern blot analyses demonstrate that only one subclass is transcribed during the parasite's asexual erythrocyte life cycle.</description><subject>58S rRNA gene</subject><subject>Animals</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>Blotting, Northern</subject><subject>Blotting, Southern</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Expression Regulation</subject><subject>Genic rearrangement. Recombination. Transposable element</subject><subject>Genomic Library</subject><subject>Molecular and cellular biology</subject><subject>Molecular genetics</subject><subject>Molecular Sequence Data</subject><subject>Multigene Family - genetics</subject><subject>Plasmodium falciparum</subject><subject>Plasmodium falciparum - genetics</subject><subject>Plasmodium falciparum - growth & development</subject><subject>Ribosomal RNA transcription</subject><subject>RNA, Ribosomal - genetics</subject><subject>RNA, Ribosomal, 5.8S - genetics</subject><subject>Sequence Homology, Nucleic Acid</subject><issn>0166-6851</issn><issn>1872-9428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1r3DAQhkVI2WzS_IMGdAglOTiVbH1eCsuSNoXQlnychSyNGwXb2kje0P33tbPLHlMYMYJ55mV4EPpEyRUlVHwZnyiE4vRCk0tNSkoLdoDmVMmy0KxUh2i-R47Qcc7PhBAuhZihWUkVrQiZo7sbGCDFP9BDGDbY9h7D31WCnEPscWzw8AT4d2tzF31Yd7ixrQsrm8Yvv1L3OIU65tjZFt_9XOApJn9EH0Yqw-mun6DHb9cPy5vi9tf3H8vFbeEYlUMhmFaMC68po7zizDWKMFtaIuvKMvDSK-UrR5gGJr0WqtHUTuVELeraVSfo8zZ3leLLGvJgupAdtK3tIa6zkVqSUmr-X5ByQSotyhFkW9ClmHOCxqxS6GzaGErM5NxMQs0k1Ghi3pwbNq6d7fLXdQd-v7STPM7Pd3ObnW2bZHsX8h4TQlZc6BH7usVglPYaIJnsAvQOfEjgBuNjeP-Of9Jfm7U</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Shippen-Lentz, Dorothy</creator><creator>Afroze, Talat</creator><creator>Vezza, Anne Carmel</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>Heterogeneity and expression of the Plasmodium falciparum 5.8S ribosomal RNA genes</title><author>Shippen-Lentz, Dorothy ; Afroze, Talat ; Vezza, Anne Carmel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-6498456d91415354cf804a2a07b3a4ed7d88d3c049e47d968f91a91a9c6b6bbc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>58S rRNA gene</topic><topic>Animals</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>Blotting, Northern</topic><topic>Blotting, Southern</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene Expression Regulation</topic><topic>Genic rearrangement. Recombination. Transposable element</topic><topic>Genomic Library</topic><topic>Molecular and cellular biology</topic><topic>Molecular genetics</topic><topic>Molecular Sequence Data</topic><topic>Multigene Family - genetics</topic><topic>Plasmodium falciparum</topic><topic>Plasmodium falciparum - genetics</topic><topic>Plasmodium falciparum - growth & development</topic><topic>Ribosomal RNA transcription</topic><topic>RNA, Ribosomal - genetics</topic><topic>RNA, Ribosomal, 5.8S - genetics</topic><topic>Sequence Homology, Nucleic Acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shippen-Lentz, Dorothy</creatorcontrib><creatorcontrib>Afroze, Talat</creatorcontrib><creatorcontrib>Vezza, Anne Carmel</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular and biochemical parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shippen-Lentz, Dorothy</au><au>Afroze, Talat</au><au>Vezza, Anne Carmel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heterogeneity and expression of the Plasmodium falciparum 5.8S ribosomal RNA genes</atitle><jtitle>Molecular and biochemical parasitology</jtitle><addtitle>Mol Biochem Parasitol</addtitle><date>1990</date><risdate>1990</risdate><volume>38</volume><issue>1</issue><spage>113</spage><epage>120</epage><pages>113-120</pages><issn>0166-6851</issn><eissn>1872-9428</eissn><coden>MBIPDP</coden><abstract>The number and expression of some of the large ribosomal RNA (rRNA) gene classes present in the human malaria parasite
Plasmodium falciparum was determined. Southern blot analyses, using the 5.8S rRNA coding region as a marker, indicate that the
P. falciparum genome contains at least 5 distinct subclasses of large rRNA genes. Dideoxy sequencing of the 5.8S rRNA domain and Northern blot analyses demonstrate that only one subclass is transcribed during the parasite's asexual erythrocyte life cycle.</abstract><cop>Shannon</cop><pub>Elsevier B.V</pub><pmid>2181300</pmid><doi>10.1016/0166-6851(90)90211-4</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Molecular and biochemical parasitology, 1990, Vol.38 (1), p.113-120 |
| issn | 0166-6851 1872-9428 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79702795 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | 58S rRNA gene Animals Base Sequence Biological and medical sciences Blotting, Northern Blotting, Southern Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genic rearrangement. Recombination. Transposable element Genomic Library Molecular and cellular biology Molecular genetics Molecular Sequence Data Multigene Family - genetics Plasmodium falciparum Plasmodium falciparum - genetics Plasmodium falciparum - growth & development Ribosomal RNA transcription RNA, Ribosomal - genetics RNA, Ribosomal, 5.8S - genetics Sequence Homology, Nucleic Acid |
| title | Heterogeneity and expression of the Plasmodium falciparum 5.8S ribosomal RNA genes |
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