Factors Affecting Bone Demineralization and Blood Lead Levels of Postmenopausal Women—A Population-Based Study from Germany
We investigated the influence of various lifestyle factors on blood lead levels in postmenopausal women from the general population of Germany. Particular consideration was given to those factors which are suspected to be related to bone demineralization. The study population consisted of 424 women,...
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| Veröffentlicht in: | Environmental research 1998-01, Vol.76 (1), p.19-25 |
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| creator | Weyermann, Maria Brenner, Hermann |
| description | We investigated the influence of various lifestyle factors on blood lead levels in postmenopausal women from the general population of Germany. Particular consideration was given to those factors which are suspected to be related to bone demineralization. The study population consisted of 424 women, aged 45 to 80 years, who were examined in a substudy of the National Health and Nutrition Survey called VERA (Verbundstudie Ernährungserhebung, und Risikofaktorenanalyse) from 1987 to 1988. Mean blood lead level was 61.4 μg/liter (SD, 27.3). In multiple linear regression analysis alcohol consumption, former use of oral contraception, hematocrit, and age were positively associated with blood lead levels, whereas calcium intake and high physical activity showed a negative association with blood lead levels. Some of the identified risk factors which are suspected to exert their influence on blood lead levels by affecting bone demineralization can be influenced by change of individual behavior. Thus, we conclude that reduction of alcohol consumption, adequate calcium intake, and physical activity may reduce blood lead levels as well as negative health effects of osteoporosis in postmenopausal women. |
| doi_str_mv | 10.1006/enrs.1997.3780 |
| format | Article |
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Particular consideration was given to those factors which are suspected to be related to bone demineralization. The study population consisted of 424 women, aged 45 to 80 years, who were examined in a substudy of the National Health and Nutrition Survey called VERA (Verbundstudie Ernährungserhebung, und Risikofaktorenanalyse) from 1987 to 1988. Mean blood lead level was 61.4 μg/liter (SD, 27.3). In multiple linear regression analysis alcohol consumption, former use of oral contraception, hematocrit, and age were positively associated with blood lead levels, whereas calcium intake and high physical activity showed a negative association with blood lead levels. Some of the identified risk factors which are suspected to exert their influence on blood lead levels by affecting bone demineralization can be influenced by change of individual behavior. Thus, we conclude that reduction of alcohol consumption, adequate calcium intake, and physical activity may reduce blood lead levels as well as negative health effects of osteoporosis in postmenopausal women.</description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1006/enrs.1997.3780</identifier><identifier>PMID: 9466893</identifier><identifier>CODEN: ENVRAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Analysis of Variance ; Biological and medical sciences ; Bone Demineralization, Pathologic - blood ; Bone Demineralization, Pathologic - epidemiology ; Chemical and industrial products toxicology. Toxic occupational diseases ; Demography ; epidemiology ; Female ; Germany ; Humans ; lead ; Lead - blood ; Life Style ; Medical sciences ; Metals and various inorganic compounds ; Middle Aged ; Multivariate Analysis ; osteoporosis risk factors ; postmenopausal women ; Risk Factors ; Sociology ; Space life sciences ; Toxicology</subject><ispartof>Environmental research, 1998-01, Vol.76 (1), p.19-25</ispartof><rights>1998 Academic Press</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c399t-d051cb84a1fc09c1cf1db015bf77a04b50e8d86ae4be2a31f0daad6861d4148f3</citedby><cites>FETCH-LOGICAL-c399t-d051cb84a1fc09c1cf1db015bf77a04b50e8d86ae4be2a31f0daad6861d4148f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1006/enrs.1997.3780$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,4021,27921,27922,27923,45993</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2167024$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9466893$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weyermann, Maria</creatorcontrib><creatorcontrib>Brenner, Hermann</creatorcontrib><title>Factors Affecting Bone Demineralization and Blood Lead Levels of Postmenopausal Women—A Population-Based Study from Germany</title><title>Environmental research</title><addtitle>Environ Res</addtitle><description>We investigated the influence of various lifestyle factors on blood lead levels in postmenopausal women from the general population of Germany. Particular consideration was given to those factors which are suspected to be related to bone demineralization. The study population consisted of 424 women, aged 45 to 80 years, who were examined in a substudy of the National Health and Nutrition Survey called VERA (Verbundstudie Ernährungserhebung, und Risikofaktorenanalyse) from 1987 to 1988. Mean blood lead level was 61.4 μg/liter (SD, 27.3). In multiple linear regression analysis alcohol consumption, former use of oral contraception, hematocrit, and age were positively associated with blood lead levels, whereas calcium intake and high physical activity showed a negative association with blood lead levels. Some of the identified risk factors which are suspected to exert their influence on blood lead levels by affecting bone demineralization can be influenced by change of individual behavior. Thus, we conclude that reduction of alcohol consumption, adequate calcium intake, and physical activity may reduce blood lead levels as well as negative health effects of osteoporosis in postmenopausal women.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis of Variance</subject><subject>Biological and medical sciences</subject><subject>Bone Demineralization, Pathologic - blood</subject><subject>Bone Demineralization, Pathologic - epidemiology</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Demography</subject><subject>epidemiology</subject><subject>Female</subject><subject>Germany</subject><subject>Humans</subject><subject>lead</subject><subject>Lead - blood</subject><subject>Life Style</subject><subject>Medical sciences</subject><subject>Metals and various inorganic compounds</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>osteoporosis risk factors</subject><subject>postmenopausal women</subject><subject>Risk Factors</subject><subject>Sociology</subject><subject>Space life sciences</subject><subject>Toxicology</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc-KFDEQh4Mo67h69SbkIN56TE3_Sec4s7qrMKCg4jFUJxWJdCdj0r0wguBD-IQ-id3OsDfxUkXx-6oI-Rh7CmINQjQvKaS8BqXkupStuMdWIFRTCFWX99lKCCgLVdbwkD3K-es8Ql2KC3ahqqZpVbliP67RjDFlvnWOzOjDF76LgfgrGnyghL3_jqOPgWOwfNfHaPmecCm31GceHX8f8zhQiAecMvb8c5yH3z9_befgMPV_l4sdZrL8wzjZI3cpDvyG0oDh-Jg9cNhnenLul-zT9euPV2-K_bubt1fbfWFKpcbCihpM11YIzghlwDiwnYC6c1KiqLpaUGvbBqnqaIMlOGERbdM2YCuoWldeshenu4cUv02URz34bKjvMVCcspaqURKk-i8IEgRIKWZwfQJNijkncvqQ_IDpqEHoRYxexOhFjF7EzAvPzpenbiB7h59NzPnzc47ZYO8SBuPzHbaBRopNNWPtCZt_n249JZ2Np2DI-jT70zb6f73gD192rHo</recordid><startdate>199801</startdate><enddate>199801</enddate><creator>Weyermann, Maria</creator><creator>Brenner, Hermann</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>199801</creationdate><title>Factors Affecting Bone Demineralization and Blood Lead Levels of Postmenopausal Women—A Population-Based Study from Germany</title><author>Weyermann, Maria ; Brenner, Hermann</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-d051cb84a1fc09c1cf1db015bf77a04b50e8d86ae4be2a31f0daad6861d4148f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analysis of Variance</topic><topic>Biological and medical sciences</topic><topic>Bone Demineralization, Pathologic - blood</topic><topic>Bone Demineralization, Pathologic - epidemiology</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Demography</topic><topic>epidemiology</topic><topic>Female</topic><topic>Germany</topic><topic>Humans</topic><topic>lead</topic><topic>Lead - blood</topic><topic>Life Style</topic><topic>Medical sciences</topic><topic>Metals and various inorganic compounds</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>osteoporosis risk factors</topic><topic>postmenopausal women</topic><topic>Risk Factors</topic><topic>Sociology</topic><topic>Space life sciences</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weyermann, Maria</creatorcontrib><creatorcontrib>Brenner, Hermann</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>Environmental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weyermann, Maria</au><au>Brenner, Hermann</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Affecting Bone Demineralization and Blood Lead Levels of Postmenopausal Women—A Population-Based Study from Germany</atitle><jtitle>Environmental research</jtitle><addtitle>Environ Res</addtitle><date>1998-01</date><risdate>1998</risdate><volume>76</volume><issue>1</issue><spage>19</spage><epage>25</epage><pages>19-25</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><coden>ENVRAL</coden><abstract>We investigated the influence of various lifestyle factors on blood lead levels in postmenopausal women from the general population of Germany. Particular consideration was given to those factors which are suspected to be related to bone demineralization. The study population consisted of 424 women, aged 45 to 80 years, who were examined in a substudy of the National Health and Nutrition Survey called VERA (Verbundstudie Ernährungserhebung, und Risikofaktorenanalyse) from 1987 to 1988. Mean blood lead level was 61.4 μg/liter (SD, 27.3). In multiple linear regression analysis alcohol consumption, former use of oral contraception, hematocrit, and age were positively associated with blood lead levels, whereas calcium intake and high physical activity showed a negative association with blood lead levels. Some of the identified risk factors which are suspected to exert their influence on blood lead levels by affecting bone demineralization can be influenced by change of individual behavior. Thus, we conclude that reduction of alcohol consumption, adequate calcium intake, and physical activity may reduce blood lead levels as well as negative health effects of osteoporosis in postmenopausal women.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>9466893</pmid><doi>10.1006/enrs.1997.3780</doi><tpages>7</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Analysis of Variance Biological and medical sciences Bone Demineralization, Pathologic - blood Bone Demineralization, Pathologic - epidemiology Chemical and industrial products toxicology. Toxic occupational diseases Demography epidemiology Female Germany Humans lead Lead - blood Life Style Medical sciences Metals and various inorganic compounds Middle Aged Multivariate Analysis osteoporosis risk factors postmenopausal women Risk Factors Sociology Space life sciences Toxicology |
| title | Factors Affecting Bone Demineralization and Blood Lead Levels of Postmenopausal Women—A Population-Based Study from Germany |
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