Design of a 13c {1h} rf probe for monitoring the in vivo metabolism of [1-13c] glucose in primate brain
The design of an RF probe suitable for obtaining proton‐decoupled 13C spectra from a subhuman primate brain is described. Two orthogonal saddle coils, one tuned to the resonant frequency of 13C and the other to the resonant frequency of 1H, were used to monitor the in vivo metabolism of [1‐13C] gluc...
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| Veröffentlicht in: | Magnetic resonance in medicine 1990-01, Vol.13 (1), p.1-5 |
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| container_title | Magnetic resonance in medicine |
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| creator | Hammer, B. E. Sacks, W. Bigler, R. E. Hennessy, M. J. Sacks, S. Fleischer, A. Zanzonico, P. B |
| description | The design of an RF probe suitable for obtaining proton‐decoupled 13C spectra from a subhuman primate brain is described. Two orthogonal saddle coils, one tuned to the resonant frequency of 13C and the other to the resonant frequency of 1H, were used to monitor the in vivo metabolism of [1‐13C] glucose in rhesus monkey brain at 2.1 T. Difference spectra showed the appearance of 13C‐enriched glutamate and glutamine 30 to 40 min after a bolus injection of [ 1‐ 13C] glucose. |
| doi_str_mv | 10.1002/mrm.1910130102 |
| format | Article |
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Difference spectra showed the appearance of 13C‐enriched glutamate and glutamine 30 to 40 min after a bolus injection of [ 1‐ 13C] glucose.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Brain - metabolism</subject><subject>Carbon Isotopes</subject><subject>Glucose - metabolism</subject><subject>Hydrogen</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Macaca mulatta</subject><subject>Magnetic Resonance Spectroscopy - instrumentation</subject><subject>Magnetic Resonance Spectroscopy - methods</subject><subject>Medical sciences</subject><subject>Nervous system</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. 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B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Design of a 13c {1h} rf probe for monitoring the in vivo metabolism of [1-13c] glucose in primate brain</atitle><jtitle>Magnetic resonance in medicine</jtitle><addtitle>Magn. Reson. Med</addtitle><date>1990-01</date><risdate>1990</risdate><volume>13</volume><issue>1</issue><spage>1</spage><epage>5</epage><pages>1-5</pages><issn>0740-3194</issn><eissn>1522-2594</eissn><coden>MRMEEN</coden><abstract>The design of an RF probe suitable for obtaining proton‐decoupled 13C spectra from a subhuman primate brain is described. Two orthogonal saddle coils, one tuned to the resonant frequency of 13C and the other to the resonant frequency of 1H, were used to monitor the in vivo metabolism of [1‐13C] glucose in rhesus monkey brain at 2.1 T. Difference spectra showed the appearance of 13C‐enriched glutamate and glutamine 30 to 40 min after a bolus injection of [ 1‐ 13C] glucose.</abstract><cop>Baltimore</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2157125</pmid><doi>10.1002/mrm.1910130102</doi><tpages>5</tpages></addata></record> |
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| ispartof | Magnetic resonance in medicine, 1990-01, Vol.13 (1), p.1-5 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals Biological and medical sciences Brain - metabolism Carbon Isotopes Glucose - metabolism Hydrogen Investigative techniques, diagnostic techniques (general aspects) Macaca mulatta Magnetic Resonance Spectroscopy - instrumentation Magnetic Resonance Spectroscopy - methods Medical sciences Nervous system Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Protons |
| title | Design of a 13c {1h} rf probe for monitoring the in vivo metabolism of [1-13c] glucose in primate brain |
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