Peptide ligand-induced conformation and surface expression of the Ld class I MHC molecule

NEWLY synthesized major histocompatibility complex (MHC) class I molecules in the endoplasmic reticulum are thought to bind peptides of foreign and endogenous antigens 1–4 . Several lines of evidence indicate that β-2 microglobulin (β 2 m) and/or peptide ligand participate in the intracellular trans...

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