Antisense basic fibroblast growth factor gene transfer reduces early intimal thickening in a rabbit femoral artery balloon injury model

Purpose: The purpose of this study was to determine whether endogenous basic fibro-blast growth factor (bFGF) production contributes to the intimal hyperplastic response to injury in a model of rabbit femoral artery balloon injury. Inhibition of de novo production of bFGF protein was targeted by int...

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Veröffentlicht in:	Journal of vascular surgery 1998, Vol.27 (1), p.126-134
Hauptverfasser:	Neschis, David G., Safford, Shawn D., Hanna, Abigail K., Fox, Jonathan C., Golden, Michael A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae Animals Antisense Elements (Genetics) - genetics Biological and medical sciences Catheterization Cell Division Diseases of the cardiovascular system Femoral Artery - pathology Fibroblast Growth Factor 2 - genetics Fibroblast Growth Factor 2 - physiology Gene Transfer Techniques Genes, Reporter Genetic Vectors Hyperplasia Lac Operon Medical sciences Rabbits Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Tunica Intima - pathology Tunica Media - pathology
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