Increased renal clearance of cefsulodin due to higher glomerular filtration rate in cystic fibrosis

The steady-state renal clearance of cefsulodin was studied in 6 patients with cystic fibrosis and 8 healthy controls. The drug was administered by constant rate infusion to obtain 2 values of plasma concentration, 2 and 30 mg/L. As an estimate of the glomerular filtration rate, the renal clearance o...

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Veröffentlicht in:	Clinical pharmacokinetics 1990-02, Vol.18 (2), p.168-175
Hauptverfasser:	HEDMAN, A, ALVAN, G, STRANDVIK, B, ARVIDSSON, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Cefsulodin - blood Cefsulodin - pharmacokinetics Cefsulodin - urine Cystic Fibrosis - metabolism Cystic Fibrosis - physiopathology Female Glomerular Filtration Rate Humans Insulin - blood Insulin - urine Kidney - metabolism Male Medical sciences Metabolic Clearance Rate Pharmacology. Drug treatments
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