The antibacterial efficacy of econazole nitrate in interdigital toe web infections
Twenty-four patients with severe interdigital toe web infections and no evidence of dermatophyte colonization received randomized treatment with either econazole nitrate (Spectazole) or its vehicle. Of the patients treated with econazole nitrate, 88% had good to excellent responses, whereas no patie...
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| Veröffentlicht in: | Journal of the American Academy of Dermatology 1990-04, Vol.22 (4), p.583-586 |
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| container_title | Journal of the American Academy of Dermatology |
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| creator | Kates, S.G. Myung, K.B. McGinley, K.J. Leyden, J.J. |
| description | Twenty-four patients with severe interdigital toe web infections and no evidence of dermatophyte colonization received randomized treatment with either econazole nitrate (Spectazole) or its vehicle. Of the patients treated with econazole nitrate, 88% had good to excellent responses, whereas no patient treated with the vehicle showed improvement. The total aerobic flora in the econazole group decreased 93%, with decreases in the large-colony diphtheroids, lipophilic diphtheroids, and gram-negative bacteria. The results of this study demonstrate that the antibacterial activity of econazole nitrate makes it an effective agent for the treatment of severe interdigital bacterial infections uncomplicated by dermatophyte colonization. |
| doi_str_mv | 10.1016/0190-9622(90)70076-T |
| format | Article |
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| ispartof | Journal of the American Academy of Dermatology, 1990-04, Vol.22 (4), p.583-586 |
| issn | 0190-9622 1097-6787 |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Aged Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Bacterial Infections - drug therapy Biological and medical sciences Econazole - therapeutic use Foot Dermatoses - drug therapy Humans Imidazoles - therapeutic use Male Medical sciences Middle Aged Pharmacology. Drug treatments Skin Diseases, Infectious - drug therapy Toes |
| title | The antibacterial efficacy of econazole nitrate in interdigital toe web infections |
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