Effects of Adrenergic Stimulation on Postnatal Development and Calcium Current in Newborn Rat Cardiomyocytes in Primary Culture

With a primary culture of ventricular cardiomyocytes from newborn rats as an in vitro model, the long-term effects of norepinephrine (NE) on hypertrophic postnatal development and the I/V properties of L-type calcium currents were investigated with the whole-cell configuration of patch-clamp techniq...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1998-02, Vol.31 (2), p.262-270
Hauptverfasser:	Pignier, Christophe, Fares, Nassim, Potreau, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology Adrenergic beta-Antagonists - pharmacology Animals Animals, Newborn Biological and medical sciences Calcium Channels - drug effects Calcium Channels - metabolism Cell Membrane - drug effects Cell Membrane - metabolism Cells, Cultured - drug effects Fundamental and applied biological sciences. Psychology Heart Heart Ventricles - cytology Heart Ventricles - drug effects Heart Ventricles - growth & development Norepinephrine - pharmacology Norepinephrine - physiology Patch-Clamp Techniques Propranolol - pharmacology Rats Receptors, Adrenergic, alpha - metabolism Time Factors Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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