Kinetics of phospholipase A2, arachidonic acid, and eicosanoid appearance in mouse zymosan peritonitis

Intraperitoneal injection of zymosan into mice induces a peritonitis characterized by cellular influx, plasma leakage and the appearance of arachidonic acid (AA) metabolites. We report that zymosan injection also stimulates the accumulation of AA, docosahexaenoic acid, linoleic acid, and phospholipa...

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Veröffentlicht in:	The Journal of immunology (1950) 1990-04, Vol.144 (7), p.2671-2677
Hauptverfasser:	Lundy, SR, Dowling, RL, Stevens, TM, Kerr, JS, Mackin, WM, Gans, KR
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acid Arachidonic Acids - metabolism Ascitic Fluid - metabolism Biological and medical sciences Chromatography, High Pressure Liquid Eicosanoids - metabolism Exudates and Transudates - metabolism Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Inflammation Male Mice Mice, Inbred Strains Molecular and cellular biology Peritonitis - metabolism Phospholipases - metabolism Phospholipases A - metabolism Phospholipases A2 Radioimmunoassay Time Factors Zymosan
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