Diazepam's Impact on Self-Stimulation but Not Stimulation-Escape Suggests Hedonic Modulation

In rats that self-administered lateral hypothalamic (LH) stimulation through chronically implanted electrodes, ip diazepam (DZ) increased rates and decreased thresholds of self-stimulation (SS) in a dose-related manner. Stimulation-escape (SE), however, was refractory to the drug. There was a comple...

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Veröffentlicht in:	Behavioral neuroscience 1990-02, Vol.104 (1), p.56-61
Hauptverfasser:	Carden, Susan E, Coons, Edgar E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Animal behavior Animal Escape Behavior Animals Arousal - drug effects Brain Mapping Diazepam Diazepam - pharmacology Dose-Response Relationship, Drug Drug Dosages Drugs Electric Stimulation Escape Reaction - drug effects Hypothalamic Area, Lateral - drug effects Hypothalamus Male Medial Forebrain Bundle - drug effects Motivation Pleasure Rats Rats, Inbred Strains Reaction Time - drug effects Rodents Self Stimulation - drug effects Self-Stimulation
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