Balloon dilatation of the stenosed aortic valve: How does it work? Why does it fail?
The hemodynamic changes that may occur in patients undergoing aortic balloon valvuloplasty were examined in the circulatory model. Four conclusions were reached. (1) Significant transvalvular pressure gradients appear only if the orifice is severely narrowed. (2) The magnitude of this gradient is hi...
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| Veröffentlicht in: | The American journal of cardiology 1990-03, Vol.65 (11), p.761-766 |
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| container_issue | 11 |
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| container_title | The American journal of cardiology |
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| creator | Robicsek, Francis Harbold, Norris B. Scotten, Lawrence N. Walker, David K. |
| description | The hemodynamic changes that may occur in patients undergoing aortic balloon valvuloplasty were examined in the circulatory model. Four conclusions were reached. (1) Significant transvalvular pressure gradients appear only if the orifice is severely narrowed. (2) The magnitude of this gradient is highly flow dependent. (3) At critical narrowings, minute alterations in orifice size may induce most significant changes in the transvalvular gradient. (4) In low flow states significant gradients appear only if the stenosis is extreme. In patients with aortic stenosis, especially those with failing hearts and low cardiac output, the pressure gradient may be effectively decreased by minimal dilatation of the aortic orifice. These patients, however, remain in jeopardy because recurrent narrowing may cause a gradient incompatible with life. |
| doi_str_mv | 10.1016/0002-9149(90)91384-I |
| format | Article |
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Why does it fail?</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>The hemodynamic changes that may occur in patients undergoing aortic balloon valvuloplasty were examined in the circulatory model. Four conclusions were reached. (1) Significant transvalvular pressure gradients appear only if the orifice is severely narrowed. (2) The magnitude of this gradient is highly flow dependent. (3) At critical narrowings, minute alterations in orifice size may induce most significant changes in the transvalvular gradient. (4) In low flow states significant gradients appear only if the stenosis is extreme. In patients with aortic stenosis, especially those with failing hearts and low cardiac output, the pressure gradient may be effectively decreased by minimal dilatation of the aortic orifice. These patients, however, remain in jeopardy because recurrent narrowing may cause a gradient incompatible with life.</description><subject>Aortic Valve - physiopathology</subject><subject>Aortic Valve Stenosis - physiopathology</subject><subject>Aortic Valve Stenosis - therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Catheterization</subject><subject>Coronary Circulation - physiology</subject><subject>Endocardial and cardiac valvular diseases</subject><subject>Heart</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Models, Cardiovascular</subject><subject>Models, Structural</subject><subject>Pressure</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFPGzEQha2qFU1p_0Er-QJqDwv2ene95gBqEYVISL1Q9WgN9li4OGuwnSD-PU4ThVtPM-N58_T8EfKZsyPO-HDMGGsbxTv1VbFviouxa-ZvyIyPUjW8zm_JbCd5Tz7k_LeOnPfDHtlrBR-6Xs7IzQ8IIcaJWh-gQPG1jY6WO6S54BQzWgoxFW_oCsIKT-hVfKI2Yqa-0KeY7s_on7vn3YsDH84-kncOQsZP27pPfv-8uDm_aq5_Xc7Pv183RoyyNNbIvmVtjdoKhoNz0rqar2PQ8nHsDUel8FZ1fS9ZB8IoJ0cLg1IggQvXiX1yuPF9SPFxibnohc8GQ4AJ4zJrqYZxqB-twm4jNCnmnNDph-QXkJ41Z3oNU69J6TUprZj-B1PP69mXrf_ydoF2d7SlV_cH2z1kA8ElmIzPr95KMNHLvupONzqsMFYek87G42TQ-oSmaBv9_4O8AC35jrg</recordid><startdate>19900315</startdate><enddate>19900315</enddate><creator>Robicsek, Francis</creator><creator>Harbold, Norris B.</creator><creator>Scotten, Lawrence N.</creator><creator>Walker, David K.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900315</creationdate><title>Balloon dilatation of the stenosed aortic valve: How does it work? 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Vascular system</topic><topic>Catheterization</topic><topic>Coronary Circulation - physiology</topic><topic>Endocardial and cardiac valvular diseases</topic><topic>Heart</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Models, Cardiovascular</topic><topic>Models, Structural</topic><topic>Pressure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Robicsek, Francis</creatorcontrib><creatorcontrib>Harbold, Norris B.</creatorcontrib><creatorcontrib>Scotten, Lawrence N.</creatorcontrib><creatorcontrib>Walker, David K.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Robicsek, Francis</au><au>Harbold, Norris B.</au><au>Scotten, Lawrence N.</au><au>Walker, David K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Balloon dilatation of the stenosed aortic valve: How does it work? Why does it fail?</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1990-03-15</date><risdate>1990</risdate><volume>65</volume><issue>11</issue><spage>761</spage><epage>766</epage><pages>761-766</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>The hemodynamic changes that may occur in patients undergoing aortic balloon valvuloplasty were examined in the circulatory model. Four conclusions were reached. (1) Significant transvalvular pressure gradients appear only if the orifice is severely narrowed. (2) The magnitude of this gradient is highly flow dependent. (3) At critical narrowings, minute alterations in orifice size may induce most significant changes in the transvalvular gradient. (4) In low flow states significant gradients appear only if the stenosis is extreme. 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| ispartof | The American journal of cardiology, 1990-03, Vol.65 (11), p.761-766 |
| issn | 0002-9149 1879-1913 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Aortic Valve - physiopathology Aortic Valve Stenosis - physiopathology Aortic Valve Stenosis - therapy Biological and medical sciences Cardiology. Vascular system Catheterization Coronary Circulation - physiology Endocardial and cardiac valvular diseases Heart Humans Medical sciences Models, Cardiovascular Models, Structural Pressure |
| title | Balloon dilatation of the stenosed aortic valve: How does it work? Why does it fail? |
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