Adenovirus Infection in Adult Orthotopic Liver Transplant Recipients: Incidence and Clinical Significance
Adenovirus infection occurs in 10% of pediatric orthotopic liver transplant recipients; however, no cases have been described in adult liver transplant recipients. A retrospective review of 191 adults who underwent liver transplantation from January 1988 through October 1995 was done to describe the...
Gespeichert in:
| Veröffentlicht in: | The Journal of infectious diseases 1998-02, Vol.177 (2), p.459-462 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 462 |
|---|---|
| container_issue | 2 |
| container_start_page | 459 |
| container_title | The Journal of infectious diseases |
| container_volume | 177 |
| creator | McGrath, Donnie Falagas, Matthew E. Freeman, Richard Rohrer, Richard Fairchild, Ralph Colbach, Christine Snydman, David R. |
| description | Adenovirus infection occurs in 10% of pediatric orthotopic liver transplant recipients; however, no cases have been described in adult liver transplant recipients. A retrospective review of 191 adults who underwent liver transplantation from January 1988 through October 1995 was done to describe the incidence and clinical significance of adenovirus infection in this population. There were 11 (5.8%) patients with 16 cultures positive for adenovirus. Sites of isolation were urine (9), blood (2), liver biopsy (2), colonic biopsy (1), lung biopsy (1), and stool (1). Adenovirus infection was classified as either disease or asymptomatic infection. There were 7 cases of adenovirus disease (2 definite, 1 probable, and 4 possible). Disease was disseminated in 3 patients: All had pneumonia and 2 died. Of the 3 patients with pneumonia, 2 had evidence of multiorgan involvement. Adenovirus disease occurs in adult orthotopic liver transplant recipients and may be associated with significant morbidity and occasional mortality. |
| doi_str_mv | 10.1086/517375 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_79685482</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>30107411</jstor_id><sourcerecordid>30107411</sourcerecordid><originalsourceid>FETCH-LOGICAL-c453t-2ffab430d15a4eb5e7ed71c168f0fd2de21e94607bbc6e99b8a0324a546713ad3</originalsourceid><addsrcrecordid>eNqFkV1rFDEUhoNY6rbqPxCCiHdT8zXJjHfLam3pQsGuWLwJmcwZzTqbmSaZUv-9KbuM4E2vEnievLw5B6HXlJxRUskPJVVclc_QgpZcFVJS_hwtCGGsoFVdv0AnMW4JIYJLdYyOayFl9hbILVvww70LU8SXvgOb3OCx83jZTn3C1yH9GtIwOovX7h4C3gTj49gbn_BXsG504FP8mJ9al4MsYONbvOqdd9b0-Mb99K7L10xeoqPO9BFeHc5T9O3882Z1Uayvv1yuluvCipKngnWdaQQnLS2NgKYEBa2ilsqqI13LWmAUcnuimsZKqOumMoQzYUohFeWm5afo_T53DMPdBDHpnYsW-twZhilqVcuqFBV7UqSS1UQKkcW3_4nbYQo-f0IzxmvKZW4-p9kwxBig02NwOxP-aEr044b0fkNZfHNIm5odtLN2WEnm7w7cxDzDLg_cujhrjIqqpNW_mG1MQ5gxJ5QoQWnmxZ67mOBh5ib81vKxh764_aHPb69W38XNJ73hfwG0k7AR</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>223913645</pqid></control><display><type>article</type><title>Adenovirus Infection in Adult Orthotopic Liver Transplant Recipients: Incidence and Clinical Significance</title><source>Jstor Complete Legacy</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><creator>McGrath, Donnie ; Falagas, Matthew E. ; Freeman, Richard ; Rohrer, Richard ; Fairchild, Ralph ; Colbach, Christine ; Snydman, David R.</creator><creatorcontrib>McGrath, Donnie ; Falagas, Matthew E. ; Freeman, Richard ; Rohrer, Richard ; Fairchild, Ralph ; Colbach, Christine ; Snydman, David R.</creatorcontrib><description>Adenovirus infection occurs in 10% of pediatric orthotopic liver transplant recipients; however, no cases have been described in adult liver transplant recipients. A retrospective review of 191 adults who underwent liver transplantation from January 1988 through October 1995 was done to describe the incidence and clinical significance of adenovirus infection in this population. There were 11 (5.8%) patients with 16 cultures positive for adenovirus. Sites of isolation were urine (9), blood (2), liver biopsy (2), colonic biopsy (1), lung biopsy (1), and stool (1). Adenovirus infection was classified as either disease or asymptomatic infection. There were 7 cases of adenovirus disease (2 definite, 1 probable, and 4 possible). Disease was disseminated in 3 patients: All had pneumonia and 2 died. Of the 3 patients with pneumonia, 2 had evidence of multiorgan involvement. Adenovirus disease occurs in adult orthotopic liver transplant recipients and may be associated with significant morbidity and occasional mortality.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1086/517375</identifier><identifier>PMID: 9466537</identifier><identifier>CODEN: JIDIAQ</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Adenoviridae - growth & development ; Adenoviridae - isolation & purification ; Adenoviridae infections ; Adenovirus Infections, Human - blood ; Adenovirus Infections, Human - epidemiology ; Adenovirus Infections, Human - urine ; Adenoviruses ; Adolescent ; Adult ; Biological and medical sciences ; Biopsies ; Biopsy ; Cells, Cultured ; Colon - virology ; Concise Communications ; Feces - virology ; Hepatitis ; Humans ; Incidence ; Infections ; Liver ; Liver - virology ; Liver Transplantation - adverse effects ; Liver, biliary tract, pancreas, portal circulation, spleen ; Lung - virology ; Medical sciences ; Middle Aged ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - mortality ; Retrospective Studies ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the digestive system ; Transplantation ; Urine ; Urologic diseases ; Viruses</subject><ispartof>The Journal of infectious diseases, 1998-02, Vol.177 (2), p.459-462</ispartof><rights>1998 INIST-CNRS</rights><rights>Copyright University of Chicago, acting through its Press Feb 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c453t-2ffab430d15a4eb5e7ed71c168f0fd2de21e94607bbc6e99b8a0324a546713ad3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/30107411$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/30107411$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2148518$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9466537$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McGrath, Donnie</creatorcontrib><creatorcontrib>Falagas, Matthew E.</creatorcontrib><creatorcontrib>Freeman, Richard</creatorcontrib><creatorcontrib>Rohrer, Richard</creatorcontrib><creatorcontrib>Fairchild, Ralph</creatorcontrib><creatorcontrib>Colbach, Christine</creatorcontrib><creatorcontrib>Snydman, David R.</creatorcontrib><title>Adenovirus Infection in Adult Orthotopic Liver Transplant Recipients: Incidence and Clinical Significance</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>Adenovirus infection occurs in 10% of pediatric orthotopic liver transplant recipients; however, no cases have been described in adult liver transplant recipients. A retrospective review of 191 adults who underwent liver transplantation from January 1988 through October 1995 was done to describe the incidence and clinical significance of adenovirus infection in this population. There were 11 (5.8%) patients with 16 cultures positive for adenovirus. Sites of isolation were urine (9), blood (2), liver biopsy (2), colonic biopsy (1), lung biopsy (1), and stool (1). Adenovirus infection was classified as either disease or asymptomatic infection. There were 7 cases of adenovirus disease (2 definite, 1 probable, and 4 possible). Disease was disseminated in 3 patients: All had pneumonia and 2 died. Of the 3 patients with pneumonia, 2 had evidence of multiorgan involvement. Adenovirus disease occurs in adult orthotopic liver transplant recipients and may be associated with significant morbidity and occasional mortality.</description><subject>Adenoviridae - growth & development</subject><subject>Adenoviridae - isolation & purification</subject><subject>Adenoviridae infections</subject><subject>Adenovirus Infections, Human - blood</subject><subject>Adenovirus Infections, Human - epidemiology</subject><subject>Adenovirus Infections, Human - urine</subject><subject>Adenoviruses</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Biopsies</subject><subject>Biopsy</subject><subject>Cells, Cultured</subject><subject>Colon - virology</subject><subject>Concise Communications</subject><subject>Feces - virology</subject><subject>Hepatitis</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infections</subject><subject>Liver</subject><subject>Liver - virology</subject><subject>Liver Transplantation - adverse effects</subject><subject>Liver, biliary tract, pancreas, portal circulation, spleen</subject><subject>Lung - virology</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pneumonia, Viral - diagnosis</subject><subject>Pneumonia, Viral - mortality</subject><subject>Retrospective Studies</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the digestive system</subject><subject>Transplantation</subject><subject>Urine</subject><subject>Urologic diseases</subject><subject>Viruses</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkV1rFDEUhoNY6rbqPxCCiHdT8zXJjHfLam3pQsGuWLwJmcwZzTqbmSaZUv-9KbuM4E2vEnievLw5B6HXlJxRUskPJVVclc_QgpZcFVJS_hwtCGGsoFVdv0AnMW4JIYJLdYyOayFl9hbILVvww70LU8SXvgOb3OCx83jZTn3C1yH9GtIwOovX7h4C3gTj49gbn_BXsG504FP8mJ9al4MsYONbvOqdd9b0-Mb99K7L10xeoqPO9BFeHc5T9O3882Z1Uayvv1yuluvCipKngnWdaQQnLS2NgKYEBa2ilsqqI13LWmAUcnuimsZKqOumMoQzYUohFeWm5afo_T53DMPdBDHpnYsW-twZhilqVcuqFBV7UqSS1UQKkcW3_4nbYQo-f0IzxmvKZW4-p9kwxBig02NwOxP-aEr044b0fkNZfHNIm5odtLN2WEnm7w7cxDzDLg_cujhrjIqqpNW_mG1MQ5gxJ5QoQWnmxZ67mOBh5ib81vKxh764_aHPb69W38XNJ73hfwG0k7AR</recordid><startdate>19980201</startdate><enddate>19980201</enddate><creator>McGrath, Donnie</creator><creator>Falagas, Matthew E.</creator><creator>Freeman, Richard</creator><creator>Rohrer, Richard</creator><creator>Fairchild, Ralph</creator><creator>Colbach, Christine</creator><creator>Snydman, David R.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19980201</creationdate><title>Adenovirus Infection in Adult Orthotopic Liver Transplant Recipients: Incidence and Clinical Significance</title><author>McGrath, Donnie ; Falagas, Matthew E. ; Freeman, Richard ; Rohrer, Richard ; Fairchild, Ralph ; Colbach, Christine ; Snydman, David R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c453t-2ffab430d15a4eb5e7ed71c168f0fd2de21e94607bbc6e99b8a0324a546713ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adenoviridae - growth & development</topic><topic>Adenoviridae - isolation & purification</topic><topic>Adenoviridae infections</topic><topic>Adenovirus Infections, Human - blood</topic><topic>Adenovirus Infections, Human - epidemiology</topic><topic>Adenovirus Infections, Human - urine</topic><topic>Adenoviruses</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Biopsies</topic><topic>Biopsy</topic><topic>Cells, Cultured</topic><topic>Colon - virology</topic><topic>Concise Communications</topic><topic>Feces - virology</topic><topic>Hepatitis</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infections</topic><topic>Liver</topic><topic>Liver - virology</topic><topic>Liver Transplantation - adverse effects</topic><topic>Liver, biliary tract, pancreas, portal circulation, spleen</topic><topic>Lung - virology</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pneumonia, Viral - diagnosis</topic><topic>Pneumonia, Viral - mortality</topic><topic>Retrospective Studies</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the digestive system</topic><topic>Transplantation</topic><topic>Urine</topic><topic>Urologic diseases</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McGrath, Donnie</creatorcontrib><creatorcontrib>Falagas, Matthew E.</creatorcontrib><creatorcontrib>Freeman, Richard</creatorcontrib><creatorcontrib>Rohrer, Richard</creatorcontrib><creatorcontrib>Fairchild, Ralph</creatorcontrib><creatorcontrib>Colbach, Christine</creatorcontrib><creatorcontrib>Snydman, David R.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McGrath, Donnie</au><au>Falagas, Matthew E.</au><au>Freeman, Richard</au><au>Rohrer, Richard</au><au>Fairchild, Ralph</au><au>Colbach, Christine</au><au>Snydman, David R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adenovirus Infection in Adult Orthotopic Liver Transplant Recipients: Incidence and Clinical Significance</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>1998-02-01</date><risdate>1998</risdate><volume>177</volume><issue>2</issue><spage>459</spage><epage>462</epage><pages>459-462</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><coden>JIDIAQ</coden><abstract>Adenovirus infection occurs in 10% of pediatric orthotopic liver transplant recipients; however, no cases have been described in adult liver transplant recipients. A retrospective review of 191 adults who underwent liver transplantation from January 1988 through October 1995 was done to describe the incidence and clinical significance of adenovirus infection in this population. There were 11 (5.8%) patients with 16 cultures positive for adenovirus. Sites of isolation were urine (9), blood (2), liver biopsy (2), colonic biopsy (1), lung biopsy (1), and stool (1). Adenovirus infection was classified as either disease or asymptomatic infection. There were 7 cases of adenovirus disease (2 definite, 1 probable, and 4 possible). Disease was disseminated in 3 patients: All had pneumonia and 2 died. Of the 3 patients with pneumonia, 2 had evidence of multiorgan involvement. Adenovirus disease occurs in adult orthotopic liver transplant recipients and may be associated with significant morbidity and occasional mortality.</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>9466537</pmid><doi>10.1086/517375</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1899 |
| ispartof | The Journal of infectious diseases, 1998-02, Vol.177 (2), p.459-462 |
| issn | 0022-1899 1537-6613 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79685482 |
| source | Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); MEDLINE |
| subjects | Adenoviridae - growth & development Adenoviridae - isolation & purification Adenoviridae infections Adenovirus Infections, Human - blood Adenovirus Infections, Human - epidemiology Adenovirus Infections, Human - urine Adenoviruses Adolescent Adult Biological and medical sciences Biopsies Biopsy Cells, Cultured Colon - virology Concise Communications Feces - virology Hepatitis Humans Incidence Infections Liver Liver - virology Liver Transplantation - adverse effects Liver, biliary tract, pancreas, portal circulation, spleen Lung - virology Medical sciences Middle Aged Pneumonia, Viral - diagnosis Pneumonia, Viral - mortality Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Transplantation Urine Urologic diseases Viruses |
| title | Adenovirus Infection in Adult Orthotopic Liver Transplant Recipients: Incidence and Clinical Significance |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T21%3A34%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adenovirus%20Infection%20in%20Adult%20Orthotopic%20Liver%20Transplant%20Recipients:%20Incidence%20and%20Clinical%20Significance&rft.jtitle=The%20Journal%20of%20infectious%20diseases&rft.au=McGrath,%20Donnie&rft.date=1998-02-01&rft.volume=177&rft.issue=2&rft.spage=459&rft.epage=462&rft.pages=459-462&rft.issn=0022-1899&rft.eissn=1537-6613&rft.coden=JIDIAQ&rft_id=info:doi/10.1086/517375&rft_dat=%3Cjstor_proqu%3E30107411%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=223913645&rft_id=info:pmid/9466537&rft_jstor_id=30107411&rfr_iscdi=true |